Surgery Benefits Older Women with Breast Cancer
In a British Journal of Surgery analysis of 18,730 older patients with estrogen receptor-positive breast cancer in the UK, the risk of dying from breast cancer was greater in patients treated with primary endocrine therapy than in those who received surgery.
For the study, researchers analyzed cancer registration data from two English regions from 2002 to 2010. Only 69 percent of women survived for 5 years if they received only endocrine therapy (anti-estrogen drugs, such as tamoxifen or aromatase inhibitors), compared with 90 percent of women who had surgery.
The study's investigators note that primary endocrine therapy is used in up to 40 percent of women in the UK with early breast cancer over age 70 years.
British Journal of Surgery, May 22, 2018