May 2002
Article Features
  Breast Cancer Risk in Twins
Boosting Cervical Screening in Chinese-American Women
Predicting Response to Chemo for Breast Cancer
First Chemotherapy, Then Tamoxifen
Exercise Prevents Bone Loss in Early Postmenopausal Women
Using Hair to Screen for Breast Cancer Debunked
The Health Insurance Choices of Medical Experts
Breast Cancer Risk in Pediatric Hodgkin's Disease Survivors
Male Breast Cancer in Ashkenazi and Sephardic Jews
Mobile Mammography Boosts Screening Rates
Medicare to Expand Coverage of Image-Guided Breast Biopsy
Removing the Ovaries to Reduce Breast and Ovarian Cancer Risk
Many Adult Cancer Survivors Lack Knowledge
Racial Disparity in Cancer Survival
No Link Between Radar Exposure and Cancer Risk
Tamoxifen Still Recommended as Breast Cancer Standard of Care


Complementry Articles
Vegetarian Diet May Protect Against Breast Cancer
New Drug to Halt Tumor Growth
FDA Clears New Radiation Option for Breast Cancer
Understanding Side Effects from Tamoxifen


Researchers Identify a New Breast Cancer Gene

Inheriting a damaged version of a gene called CHK2 nearly doubles a woman's chance of developing breast cancer, according to a study published in the journal Nature Genetics. Scientists believe the discovery may eventually bring improved genetic testing for breast cancer and could lead to new ways of treating and preventing the disease.

A faulty version of CHK2 appears to be one of a number of genes that can combine to increase the risk of breast cancer, according to the study, a collaboration between researchers at The Institute of Cancer Research and the University of Cambridge, and colleagues in the Netherlands.

Scientists already know that faults in the BRCA1 and BRCA2 genes greatly increase the chance of developing breast cancer, but these only account for about 2 per cent of cases. They believe inherited risk of breast cancer is more often caused by a combination of genes, each with a modest effect on risk. The new study suggests that a faulty version of CHK2 is one such gene.

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