December 2003
Article Features
  Secrets Behind Aging May Provide Clues for Controlling Cancer
Alcohol Use Increases the Risk of Hormonally Sensitive Breast Cancers in Postmenopausal Women
Breast Density, Exercise and Breast Cancer Risk
Financial Problems Linked to Depression Symptoms in Breast Cancer Patients
Breast Cancer Susceptibility Genes Play Role in DNA Repair
Research Finds Tumor Preventive Qualities, Damage Reversal, in Green Tea
Britain Offers Breast Cancer Screening to Hodgkin's Disease Survivors
Estrogen Has Antitumor Activity in Hormone-Therapy Resistant Breast Tumors
Imaging Technique May Diagnose Breast Cancer Without Biopsy
Study Concludes Hormone Replacement Therapy Should Be Discontinued at Breast Cancer Diagnosis
Thanksgiving: A Time for Healthful Eating
Using PET to Determine Effectiveness of Pre-Surgery Chemotherapy for Breast Cancer
Unlocking the Mysteries of a Key Breast Cancer Protein
New Study Shows Possible Role of SERMs in Future Menopausal Hormone Therapy
New Breast Cancer Test Could Predict Response to Tamoxifen and Anastrozole
The Effects of Weight Loss and Weight Gain on Biomarkers of Breast Cancer Risk
Hip-to-Waist Ratio Link Studied in Breast Cancer
Lycopene's Anti-Cancer Effect Linked to Other Tomato Components
New Study Looks at Life After Breast Cancer

High Nuclear Grade Associated with Recurrence of In Situ Breast Lesions

Women with ductal carcinoma in situ, a non-invasive form of breast cancer, are more likely to experience a recurrence after treatment if their DCIS is of a high nuclear grade or is detected by palpation during a breast examination, according to a study published in the Journal of the National Cancer Institute.

DCIS accounts for about 20% of all newly diagnosed cases of breast cancer in the United States and is initially treated surgically, either by mastectomy (removal of the entire breast) or lumpectomy (removal of the tumor and minimal surrounding tissue). Some women will experience a recurrence, but it is unclear what characteristics are associated with the risk of recurrence.

Karla Kerlikowske, M.D., of the San Francisco Veterans Affairs Medical Center, and her colleagues examined information about 1,036 women in the San Francisco Bay area who were age 40 or older when diagnosed with DCIS and treated with lumpectomy alone.

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