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Anti-Estrogen Drug Therapy Reduces Risk of Invasive Breast Cancer in Older Women
Study Suggests Chemotherapy Diminishes Fertility in Breast Cancer Patients
Blacks, Hispanics Less Likely than Whites to Receive Follow-Up Radiation for Early Breast Cancer
Eribulin Mesylate Demonstrates Anti-Tumor Activity in Patients with Advanced Breast Cancer
Familial Breast Cancer Risk Continues Throughout a Woman’s Life
Doctors Can Unmask Deceptive High-Risk Breast Tumors Using Genetic Profile
'Cool' New Treatment for Hot Flashes in Breast Cancer Survivors
Pre-Operative Assessment of Breast Cancer Patients by Physical Therapists Improves Lymphedema Diagnosis and Treatment
Low Melatonin Associated with Increased Risk of Breast Cancer in Postmenopausal Women
Molecular 'Clock' Could Predict Risk for Developing Breast Cancer
Researchers Identify Genetic Signature Profile for Metastasis
Poor Sleep a Problem in Long-Term Breast Cancer Survivors
Cancer Survivors are Living in Limbo with Unmet Needs for Care
Exercise in Adolescent and Young Women Is Associated With a Lower Risk of Premenopausal Breast Cancer
Adding Ultrasound to Mammography May Improve Breast Cancer Detection in High-Risk Women

Mammography Facility Characteristics Associated with Accuracy of Screening

Some characteristics of mammography facilities are associated with the accuracy of interpretation of screening mammograms, according to a study published in the Journal of the National Cancer Institute.

Previous studies have suggested that patient characteristics, such as age, are associated with variations in the accuracy of screening mammograms. Similarly, characteristics of the radiologist who interprets the mammograms, such as his or her reading experience, are associated with variations in accuracy. The impact of the type of facility or its characteristics on mammogram accuracy was unknown, but the information could help identify better practices and better places to obtain a mammogram.

In the current observational study, Stephen Taplin, M.D., of the National Cancer Institute in Bethesda, Md., and colleagues surveyed 53 mammography facilities between 1992 and 2002 to look for associations between facility characteristics and interpretive accuracy. The researchers were able to analyze data from 44 facilities, which altogether performed 484,463 screening mammograms on 237,669 women. Of those, 2,686 women were diagnosed with breast cancer.

On average, the facilities identified cancer when it was present (sensitivity) in 79.6 percent of breast cancer cases that occurred within one year and correctly categorized a mammogram as cancer-free (specificity) 90.2 percent of the time. The likelihood of cancer in women who were referred for additional imaging or evaluation due to an abnormal mammogram was 4.1 percent. On average, 38.8 percent of the women referred for a biopsy from each facility were found to have cancer. The likelihood of cancer among the women with any additional evaluation, or those referred for biopsy, varied substantially between facilities. The likelihood that a mammogram was accurately read as cancer-free varied by facility but the likelihood that a cancer was identified when it was present did not.

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