Breast Cancer Risk Rapidly Declines after Women Stop Taking Postmenopausal Combined Hormone Therapy

Women who stopped taking the postmenopausal hormone combination of estrogen plus progestin experienced a marked decline in breast cancer risk which was unrelated to mammography utilization change, according to a study from the Women's Health Initiative led by a Los Angeles Biomedical Research Institute (LA BioMed) investigator that was published in The New England Journal of Medicine.
"These findings support the hypothesis that the recent reduction in breast cancer incidence in the United States is predominantly related to a decrease in combined estrogen plus progestin use," said Rowan T. Chlebowski, M.D., Ph.D., a LA BioMed chief investigator and lead author for the study.