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Article Features
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Cancer Scientists Determine Mechanism of Powerful Tumor Suppressor Protein Chd5
Costly Breast Cancer Screenings Don't Add Up To Better Outcomes for Older Women
DNA-Repairing Protein May Be Key to Preventing Recurrence of Some Cancers
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First Study of Oregon's Hmong Reveals Surprising Influences on Cancer Screenings
Genetic Form of Anemia Offers New Avenue to Treating Drug-Resistant Tumors
Less Invasive Treatment is Associated with Improved Survival in Early Stage Breast Cancer
Low Vitamin D Levels Linked to High Risk of Premenopausal Breast Cancer
Molecular Pathway Holds Promise in Battling Triple-Negative Breast Cancer
New Method Identifies Genes That Can Predict Prognoses of Cancer Patients
New Method to Diagnose Hereditary Breast and Ovarian Cancers
New Test Predicts Presence of Harmful BRCA Mutations
Nobel Laureate James Watson Publishes Novel Hypothesis on Curing Late-Stage Cancers
PET/CT Shows Clear Advantages Over Conventional Staging for Breast Cancer Patients
Physicians Call for Change in Cancer Tissue Handling
Research Provides New Drug Target for HER-2 Related Breast Cancer
Researchers Discover Promising Prognostic Marker for Aggressive Breast Cancer
Researchers Find DNA Marker That Predicts Breast Cancer Recurrence
Researchers Identify Possible Drug Target for Breast Cancer Metastasis
Researchers Prevent Cancer Spread By Blocking Tissue Scarring
Researchers Reveal Aggressive Breast Cancer’s Metastatic Path
Spin and Bias in Published Studies of Breast Cancer Trials
Study Finds Qigong Improves Quality of Life for Breast Cancer Patients
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Low Vitamin D Levels Linked to High Risk of Premenopausal Breast Cancer

A prospective study led by researchers from the University of California, San Diego School of Medicine has found that low serum vitamin D levels in the months preceding diagnosis may predict a high risk of premenopausal breast cancer.

The study of blood levels of 1,200 healthy women found that women whose serum vitamin D level was low during the three-month period just before diagnosis had approximately three times the risk of breast cancer as women in the highest vitamin D group. Their findings were published in the journal Cancer Causes and Control.

Several previous studies have shown that low serum levels of vitamin D are associated with a higher risk of premenopausal breast cancer. "While the mechanisms by which vitamin D could prevent breast cancer are not fully understood, this study suggests that the association with low vitamin D in the blood is strongest late in the development of the cancer," said principal investigator Cedric Garland, DrPH, FACE, professor in the Department of Family and Preventive Medicine at UC San Diego.

Analyses of vitamin D levels measured more than 90 days before diagnosis have not conclusively established a relationship between serum levels and risk of premenopausal breast cancer in the present cohort. However, this new study points to the possibility of a relevant window of time for cancer prevention in the last three months preceding tumor diagnosis –a time physiologically critical to the growth of the tumor.

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