Current Month 2013
Article Features
  An Area’s Level of Poverty or Wealth May Affect the Distribution of Cancer Types
Breast Tomosynthesis After Screening Mammography Reduces Need for Ultrasound Biopsies
Cancer’s Potential On-Off Switch
Cognitive Behavioral or Relaxation Training Helps Women Reduce Distress During Breast Cancer Treatment
Dieting May Decrease Chances for Metastasis in Triple-Negative Breast Cancer
Discovery of How Taxol Works Could Lead to Better Anticancer Drugs
Few Women at High Risk for Hereditary Breast and Ovarian Cancer Receive Genetic Counseling
Gene Patterns Responsible for Normal Breast Tissue May Also Play A Role in Cancer Development
Large Panel Genetic Testing Produces More Questions Than Answers in Breast Cancer
Lifestyle Changes Improve Biomarkers Associated with Breast Cancer Recurrence and Mortality
More Access to Health Care May Lead to Unnecessary Mammograms
MRI Catches Breast Cancer Early in At-Risk Survivors of Childhood Hodgkin Lymphoma
‘Nanodaisies’ Deliver Drug Cocktail to Cancer Cells
New Method Sneaks Drugs Into Cancer Cells Before Triggering Release
New Paper Provides Important Insights into Carcinoma-Associated Fibroblasts
New Technology Could Take Light-Based Cancer Treatment Deep Inside the Body
New Tool to Grow Cancer Cells Streamlines Laboratory Research
New Way to Predict Response to Chemo in Triple-Negative Breast Cancer
Non-Screened Patients with Breast Cancer Need More Treatment Than Screened Patients
Overestimation of Radiation Exposure May Keep Women from Critical Screening
Researchers Develop Pilot Patient-Centered Educational and Behavioral Program to Reduce Lymphedema Risk
Researchers Identify New Functional Roles on Cell Surfaces for Estrogen
Scientists Design Molecule That Blocks Cancer Growth in Mice
Signals Found That Recruit Host Animals’ Cells, Enabling Breast Cancer Metastasis
Study Finds Most Women Who Have Double Mastectomy Don’t Need It
Study Identifies Risk of Chemotherapy-Related Hospitalization for Early-Stage Breast Cancer Patients
Team Reports Validation of Potentially Powerful New Way to Treat HER2-Positive Breast Cancer
Triple-Negative Breast Cancer Linked to Ethnicity and Socioeconomic Status
Tumor Cells in the Blood May Indicate Poor Prognosis in Early Breast Cancer
Two New Possible Drug Targets for Triple-Negative Breast Cancer


Non-Screened Patients with Breast Cancer Need More Treatment Than Screened Patients

Screening 40- to 49-year-old women for breast cancer has additional benefits beyond the proven decrease in mortality rate. Patients screened with mammography are statistically less likely to undergo chemotherapy, avoiding the associated toxic morbidities. Screening mammography also helps identify a subset of patients at increased risk of breast cancer by diagnosing high-risk lesions.

The majority of high-risk lesions identified in a retrospective chart review were found in screened patients. Identifying patients at high risk may allow for the administration of chemoprevention, decreasing the risk of subsequent breast cancer development. The identification of high-risk lesions may also lead to supplemental screening MRI, which has the added benefit of detecting future mammographically occult malignancies in high-risk patients.

"When the U.S. Preventive Services Task Force guidelines were published in 2009, confusion was created among patients and primary care providers on when and if 40- to 49-year-old women should be screened," said Nelly Salem of University Hospitals–Case Western Reserve. "Without screening mammography, these asymptomatic high-risk women would be unaware of their risk and the opportunity to decrease their risk of subsequent breast cancer development with use of chemoprevention."

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