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How Obesity Promotes Breast Cancer

Scientists from Helmholtz Zentrum München, Technische Universität München (TUM) and Heidelberg University Hospital report in the journal Cell Metabolism that obesity leads to the release of cytokines into the bloodstream, which impacts the metabolism of breast cancer cells, making them more aggressive as a result.

The team has already been able to halt this mechanism with an antibody treatment.

The number of people with obesity is increasing rapidly worldwide. The German Cancer Research Center (DKFZ) recently reported that according to the WHO the number of children and adolescents with obesity increased tenfold between 1975 and 2016. Severe overweight can lead to various health impairments. Besides inducing cardiovascular diseases, obesity also promotes the development of cancer and metastases.

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