Ask an Expert: Biological Targeted Therapy

Johns Hopkins Avon Foundation Breast Center
ForumQuestionsAsk a Question
Biological Targeted Therapy
Questions about biological targeted therapy.
184 This functionality is disabled from time to time due to volume.

Page 1 of 2 [184 questions]    Go to page 1, 2 ... 2
 Asked: 11/26/2018 I was just diagnosed with mucinous less than 2 cm.
 Asked: 8/8/2018 Hello, Are there any new studies (within the last year) regarding T1aN0, HER2+ adjuvant therapy options? My tumor was 1.5 millimeters.
 Asked: 8/7/2018 What is your opinion on DIM for previous Hormone positive breast cancer early stage 9 years out..
 Asked: 6/8/2018 I''m intereted in immunotherapy for my aunt with stage 4 breast cancer.
 Asked: 5/29/2018 I am 63 years old, stage 1b, grade 2, micro (.25mm) in sentinel node.
 Asked: 5/23/2018 I am estrogen positive HER2 negative and 2/3 positive nodes.
 Asked: 4/9/2018 Is Perjeta considered a hair loss drug? The manufacturer lists hair loss as a side effect when used with a taxane, which causes hair loss...
 Asked: 3/14/2018 I heard that the Oncotype Dx Test is not validated for rare types of breast cancer like mucinous, is that true? I know that most...
 Asked: 12/11/2017 Diagnosis was 4.5 cm with positive auxiliary node positive.
 Asked: 11/2/2017 I was diagnosed with Stage 1 IDC (HER2+, Grade 3) in 9/2016, had surgery to remove the tumor in 10/2016, had chemotherapy (ACTH) from 11/2016...
 Asked: 10/12/2017 Hello. I have been diagnosed with Stage 2A IDC.
 Asked: 7/21/2017 There has been a lot of news lately about the FDA approving Neratnib for HER2+ breast cancer.
 Asked: 7/10/2017 **I received a response to this question earlier and from the response I realized I did not clearly state that I am currently a patient...
 Asked: 7/9/2017 I am HER2 positive with a ratio of 2.0 and 95%ER and PR reactors.
 Asked: 7/3/2017 Does the standard of care recommend chemotherapy for Stage 1 breast cancer if the patient is HER2 positive? If so, are there any factors that...
 Asked: 6/21/2017 I have been treated for breast cancer 2011.It was triple positive.I was not given Inj Herceptalin.All my recent reports are normal (May 2017).
 Asked: 5/21/2017 Hello, One of my family members was diagnosed with TNBC.
 Asked: 5/17/2017 My mother has been dx with clinical staging of 2A, TNBC invasive mammary carcinoma of grade 3.
 Asked: 5/7/2017 My oconologist said chem is needed to weaken the cancer cell so herceptin can get inside the cell, but I thought herceptin initially attacked the...
 Asked: 5/3/2017 Why doctor can''t directly inject the medicine to tumor directly for killing the cancer cells, such as the way biopsy doing? is there any CRISPR...
 Asked: 4/30/2017 Hi.I am on Herceptin now.I have Her2 positive BC .
 Asked: 4/26/2017 is there any research using gene knockout to treat breast cancer? Biopsy using needle to reach the tumor, could use this way to deliver some medicine...
 Asked: 4/2/2017 I am scheduled for a breast surgery 4 days after my last dose of herceptin alone.
 Asked: 3/14/2017 I was diagnosed with Ductal Carcinoma IN-SITU (DCIS)(non-invasive or intraductal) and had lumpectomy which revealed a 4.5mm TNBC invasive cancer with good margins
 Asked: 3/12/2017 I am not sure where to put my question, I hope you can guide me, 2 years back I had mastectomy & am taking Femara...
 Asked: 3/10/2017 Lillie, is there no way to know if Tamoxifen is working? I read you can be tested for CYP2D6 to see what type of metabolizer you are.
 Asked: 3/8/2017 from Malaysia. This is for my mom.
 Asked: 2/17/2017 What is the most updated treatment with minimal side effects for metastatic breast cancer to liver and bone for her2 positive, node negative, hormone receptor...
 Asked: 2/1/2017 Hello, Also as a follow up (two questions): Is Xeloda effective for TNBC patients (after initial chemo, surgery, and radiation)? Have you heard of FoundationOne Inc
 Asked: 2/1/2017 Hello, My wife was diagnosed with TNBC (3A) back in September.
 Asked: 11/29/2016 My mom has Left breast IDC s/p left mastectomy, 1.7cm, grade3 MBR8/9, ER and PR are negative, HER2 +++, clear margins, negative LN, NO LVI.
 Asked: 11/28/2016 Why are doctors so focused on destroying or removing the Cancers.
 Asked: 11/17/2016 I was diagnosed with breast cancer. My tumor was removed via lumpectomy .
 Asked: 10/11/2016 Hello..diagnosed 4/16 IDC right breast. Tumor 2.4cm,.
 Asked: 9/22/2016 I have mbc HER2+ and have been on Herceptin for 3.5 years and have been having MUGA scans every 3 months.
 Asked: 9/2/2016 Hello 53 year old woman diagnosed stage 1 grade 1 node negative 1.5cm invasive papillary carcinoma left breast.
 Asked: 8/8/2016 Hello, My mother was diagnosed with HER2+ breast cancer last month.
 Asked: 7/10/2016 Are there any preliminary results from the Xofiga trial on breast cancer? Does it look promising?
 Asked: 6/23/2016 My mother was diagnosed with HER2+ breast cancer last month.
 Asked: 4/19/2016 I have metastatic bc with just a small amount left in the bones.-yay! However, after being on Herceptin for 3 years, my EF factor dropped...
 Asked: 4/5/2016 I have IDC, grade 3, node negative, ER+/PR+.
 Asked: 3/31/2016 53 old female patient operated in Jully 2015 for R breast cancer.
 Asked: 3/30/2016 Oncologist is recommending Fulvestrant and Palbociclib as 3rd line treatment for my MBC (bones).
 Asked: 3/3/2016 I am not sure where to put my question, I am 56 1/2 years old, I had mastectomy (left breast) in March 2014, I did...
 Asked: 2/6/2016 I sent an question the other day and left out one important word on biopsy intraductal epithelial hyperplasia fibro cystic breast with microcalificatiobs, is...
 Asked: 2/4/2016 Can you tell me what fibro cystic change with epithelial intraductal hyperplasia means and is this worrisome or normal finding?
 Asked: 2/2/2016 Can you tell me what a biopsy report findings and what it means, fibro cystic breast tissue with intraductal hyperplasia means, is this normal...
 Asked: 1/27/2016 I took Tamoxifen for 5 years following stage I breast cancer in 1998.
 Asked: 1/24/2016 Is there evidence that herceptin can cause high blood pressure? I have always had normal ranges for bp and since being on herceptin, my...
 Asked: 1/19/2016 I have been diagnosed with stage 2a bc.
 Asked: 1/12/2016 I had a 2.5 Lobular carcinoma mass removed last month.
 Asked: 11/20/2015 What does taking vitamin D3 (in various amounts) do to the effect of estrogen reduction from arimidex? .
 Asked: 10/15/2015 Where can I find PhD or MDs to ask about ADC treatments to Triple Negative Breast Cancer, particularly anti-TROP2?
 Asked: 10/9/2015 Are there any biological targeted therapies for ER- or PR- DCIS?
 Asked: 9/6/2015 I am over 65 years old,3rd time cancer diagnosis.
 Asked: 8/31/2015 Male diagnosed with primary extramammary paget''s disease of the scrotum with strong HER2 positive mutation --- Are any of your targeted therapies already developed...
 Asked: 8/14/2015 I''ve been on Herceptin for over 2 years now and never had any side effects that bothered me.
 Asked: 7/30/2015 Have you ever treated patients with breast cancer with natural means like transfer factors and nutrition? .
 Asked: 5/27/2015 I have herceptin infusion every three weeks and have been on it for 19 months (stage four at dx, Her 2 pos, estrogen pos).
 Asked: 5/19/2015 I have been on tamoxifen for approx 4 months and my body is slowly adjusting to the side effects.
 Asked: 5/17/2015 Currently on Taxotere + Cytoxan + Herceptin x 4.
 Asked: 4/26/2015 Should all HER2+ be treated with Herceptin? 51 y/o, diagnosis after lumpectomy Stage 1a, Grade 2, (intermediate nuclear grade, cribriform and solid) No node...
 Asked: 4/15/2015 I had Herceptin for 6 months, 3 months of weekly with paclitaxel, and 3 months of 3-weekly only Herceptin.
 Asked: 4/15/2015 I''m a member of Kaiser Southern Calif and diagnost with breast cancer.
 Asked: 3/22/2015 I am looking for input on a treatment decision for a 67 year old female newly diagnosed with metastatic breast cancer with mets to bones and liver.
 Asked: 3/18/2015 I was diagnosed with IDC HER2neu positive, ER 95%, PR 10%, Grade 3, 2 tumors (one was 2 cm and one was too small to...
 Asked: 1/13/2015 What are medial lesions?
 Asked: 1/11/2015 Under what conditions is Herceptin available to women w HER2+2 status?
 Asked: 1/8/2015 Do you know of any studies regarding Herceptin use for over 2 years and heart issues in MBC patients? Are the heart problems with Herceptin...
 Asked: 12/13/2014 Your answer to the previous question was incorrect.
 Asked: 12/12/2014 Herceptin given for only 6 months in Europe.
 Asked: 11/7/2014 I am 64. I have completed taxol and herceptin, 12 weeks.
 Asked: 10/22/2014 58 yo with 4mm triple positive Grade 2 IDC with adjacent comedo DCIS.
 Asked: 10/12/2014 I am currently on herceptin only every 3 weeks.
 Asked: 9/7/2014 I was diagnosted before one and a half year, with triple negative breast cancer grade III.
 Asked: 9/2/2014 My wife was daignosed with malignant well differentiated ductal carcinoma of mucoid subtype grade 1.she was in stage 2 and she had mastectomy with removal...
 Asked: 9/1/2014 I have finished my 12 week taxol/herceptin weekly infusions.
 Asked: 8/14/2014 I''m looking foe some info on killing triple negative breast cancer with a virus. My wife, 55 years old, has been diagnosed with triple negative breast...
 Asked: 7/26/2014 I had three non-immediate reactions following my first full dose of Herceptin, following 12 weeks of 1/3 doses with Taxol.
 Asked: 7/5/2014 Hi Lillie - how effective is chemotherapy (TAC) against Grade 1 IDC, 2.8 cm tumor, 1 out of three nodes positive.
 Asked: 6/24/2014 I am on Taxol and Herceptin. Pre-meds are decoodron, benedryl and pepcid.
 Asked: 6/23/2014 I will start my treatment soon of taxol and herceptin.
 Asked: 6/16/2014 I have received 4 herceptin treatments with taxol .
 Asked: 6/5/2014 I am her2+, tumor was 4.5mm, clean margins & lymph node positive.
 Asked: 5/8/2014 Relatively healthy 87 year old with Invasive Ductal Carcinoma of 8mm, ER strong positive, PR strong positive, ki-67 1-4% favorable HER2 Negative, Cribriform Architectural pattern,...
 Asked: 4/1/2014 Not really a category for this one so I''ll ask it here.
 Asked: 3/31/2014 My friend is otherwise healthy but has been told by oncologists in New Zealand there is no further treatment available for her.
 Asked: 2/25/2014 I was diagnosed with DCIS, stage 0, Grade 3.
 Asked: 1/18/2014 I am having TCH treatments for a Stage 1 Grade 3 Her2 Pos.
 Asked: 1/12/2014 Would trastuzumab therapy be indicated for a 71 year old woman with a 1.4cm HER2 negative, ER and PR positive primary breast tumor (invasive ductal...
 Asked: 1/3/2014 I was diagnosed with DCIS Stage 0.
 Asked: 12/23/2013 I am 40, pre-menopausal, one breast involved with 2.1CM, IDC grade 3, E+ 81%, P+ 46%, HER2/neu+ (3+), and ultrasound of the lymph nodes showed...
 Asked: 12/23/2013 Does Herceptin reduce the effectiveness of Tamoxifen, and if so, by how much? For pre-menopausal HER2+, E+, P+ patients, what should be done about...
 Asked: 12/23/2013 Why is Herceptin given with chemo and not on its own? For situations with no lymph node involvement (where chemo may not be required),...
 Asked: 12/9/2013 Palbiciclib- is it for both lobular and Idc? It states one requires a cd 4 & cd 6 genetic mutation.
 Asked: 10/2/2013 IHC equivocal, FISH equivocal, will CISH and or Oncotype DC confirm Her2 status? I have grade 1 invasive and had lumpectomy in August but am...
 Asked: 9/25/2013 What treatment do you recommend.
 Asked: 7/29/2013 When will the results of the FACE trial be made public? I thought it was going to be this spring?
 Asked: 6/19/2013 After 6 round chemo via bracial vien and after about 15 months of last session of chemo i have bracial vien sclerozing.
 Asked: 6/11/2013 Iam her2 negative er. Pr.

© The Johns Hopkins University, The Johns Hopkins Hospital, and Johns Hopkins Health System, All rights reserved.