Ask an Expert: Chemotherapy

Johns Hopkins Avon Foundation Breast Center
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Questions about Neoadjuvant and Adjuvant Chemotherapy.
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 Asked: 7/11/2015 In a previous question (07/10/15), it was confirmed that adjuvant chemotherapy should ideally takes place 3-4 weeks post surgery.
 Asked: 7/10/2015 I have been diagnosed with infiltrating ductal carcinoma grade II, because of the large size I have just finished chemo before surgery.
 Asked: 7/10/2015 My mother is considering receiving chemo therapy before her mastectomy (she has Stage IIA, Grade 3, estrogen receptor positive), the doctor said the treatment will...
 Asked: 7/10/2015 Age 44 diagnosed with DCIS/IDC Left breast with no differentiation in how much it was of either the DCIS or the IDC, Stage IIA, 2.6cm,...
 Asked: 7/10/2015 I have just had a second wide local excision for Grade 2 invasive ductal carcinoma.
 Asked: 7/10/2015 My mother was recently diagnosed with Stage IIA breast cancer.
 Asked: 7/9/2015 Hi there. I''m 35 and had a lumpectomy on a 5mm ILC tumor of the pleomorphic type, grade 2 (mitotic score 1, other two were 3).
 Asked: 7/8/2015 Age 53/pre-menopausal/3.7cm/Stage 2b/100%ER+/95%PR+/Her2-/DCIS invasive/1+node/bilateral mastectomy/clear margins/T2/N1A/M0/Excellent Health/Question: Hormone Therapy + Ovary Suppression OR Hormone Therapy + Chemo?
 Asked: 7/8/2015 Recently diagnosed with Stage 1 invasive duct carcinoma and had a lumpectomy in May 2015.
 Asked: 7/8/2015 Please help. I have stage 2 Breast Cancer and just finished 4 dose dense of AC chemo.
 Asked: 7/6/2015 Hello, My mother has a breast cancer with ER and PR negative and her2 neo 3+.
 Asked: 7/5/2015 If cancer return will it be metastatic even if I get chemotherapy.
 Asked: 7/4/2015 So sorry I forgot to say i had a lumpectomy in my left breast with a breast reduction thank you..
 Asked: 7/4/2015 Hi I am 60-recently diagnosed with stage1 Breast cancer,ductal invasive carcinoma 1.3cm histopathologic grade(overall)8,glandular/tubular differentiation3 nuclear pleomorphism 3 mitotic count 2 tumor focality single ductal...
 Asked: 7/4/2015 Hi, I had wide local incision on April 29th for IDC Stage 1 grade 2 Er+ / Pr- and HER - no node involvement.
 Asked: 7/1/2015 Dear Expert, I have a question about chemotherapy dose reduction.
 Asked: 6/29/2015 Oncotype score of 23 or 15%. Trying to wrap my head around report before MO appt.
 Asked: 6/29/2015 Can you explain the Stages of Breast CA: I was diagnosed Stage 2, but I thought that was when the lymph nodes were positive, and mine were negative.
 Asked: 6/29/2015 dx with Estrogen/progesterone = HER- 2 Neg Stage 2 Breast CA.
 Asked: 6/28/2015 Lillie, in reading discussion boards I see that many her2 positive patients get perjeta along with herceptin.
 Asked: 6/28/2015 I am 42 years old and had single mastectomy with one stage reconstruction.
 Asked: 6/25/2015 Mother diagnosed with Stage 2b lobular invasive carcinoma.
 Asked: 6/25/2015 My family member has a tumor described as 5 mm on initial biopsy.
 Asked: 6/25/2015 I had Oncogene Dx testing done but 1of 2 nodes were positive.
 Asked: 6/24/2015 What is your professional opinion for the management of a 53 year old women stage 2a breast Cancer, 1 out of 2 lymph nodes positive,...
 Asked: 6/24/2015 Does chemo for metastatic breast cancer always make you sick?
 Asked: 6/24/2015 I have just been diagnosed with grade 3..
 Asked: 6/24/2015 42 years old.Hysterectomy in 1999 with LT ovary removed.
 Asked: 6/23/2015 I recnetly had surgrey to remove a DCIS 1.6 cm tumor.
 Asked: 6/23/2015 I reocently received my Fterstfds My test score is 19.
 Asked: 6/23/2015 On March 26, 2014 I was diagnosed with stage 2a triple negative breast cancer.
 Asked: 6/22/2015 Lillie, please help me understand here. We are told having a low ki-67 is a good prognostic factor.
 Asked: 6/22/2015 Is Taxol still effective chemotherapy for ER positive and HER2 negative breast cancer patients? I''ve seen a couple studies (2007, 2014) that raise the question.
 Asked: 6/21/2015 I''ve been diagnosed with infiltrating moderately to poorly differentiated ducal carcinoma of the left breast3.5x3.1x3 cms.
 Asked: 6/21/2015 I''ve been diagnosed with infiltrating moderately to poorly differentiated ducal carcinoma of the left breast3.5x3.1x3 cms.
 Asked: 6/20/2015 I have a low oncotype score (14) and it says I will get zero benefit from chemo.
 Asked: 6/20/2015 I was had lumpectomy for a small tumor (0.7 centimeters).
 Asked: 6/19/2015 Can chemotherapy prevent a late recurrence (greater than 10 years)? Or is chemo really only effective for a couple of years after administration? I have...
 Asked: 6/19/2015 My chemo is neoadjuvent, but I misspoke in my question submitted yesterday regarding Taxol''s effectiveness for ER+ patients..
 Asked: 6/19/2015 57 year old partial mastectomy for IDC 1.2 cm (T1c), clean wide negative margins, 0 of 3 nodes negative for cancer.
 Asked: 6/17/2015 I am 45, IDC P+, E+, HER-, N- Onco DX 18 Tumor was 4cm.
 Asked: 6/16/2015 Maximum time interval between adjuvant chemotherapy and mastectomy.
 Asked: 6/15/2015 My mother, 84 years old, recently went through a mastectomy for TNBC.
 Asked: 6/15/2015 I had a left breast mastectomy, after being diagnosed with Stage 1, grade 2 1.5cm invasive carcinoma.
 Asked: 6/15/2015 I am 44 year old, diagnosed with IDC on my left breast, I had mastectomy, ER+,PR+HR-,lymph node-,sentinel node-,tumor size 1.2x1.2x0.7cm, oncotype 18,grade 3
 Asked: 6/14/2015 I am a 47 year old, stage 1, 1 cm tumor, grade 3, ER and PR positive, HER neg, had a lumpectomy and will have radiation and hormone therapy.
 Asked: 6/13/2015 I am 63 years old and recently diagnosed with grade 1, stage 2, ductal invasive breast cancer in right breast, tumor was 1.7 cm,...
 Asked: 6/12/2015 Hello, My mother was diagnosed with two cancers, Ca Sigmoid Colon (July, 2013) and another in Left Breast (Oct, 2013).
 Asked: 6/12/2015 Hello, I finished up 14 rounds of chemo, followed by radiation 3 months ago for right Lobular breast cancer that had traveled to...
 Asked: 6/11/2015 I have invasive ductal carcinoma, currently stage 1.
 Asked: 6/11/2015 I am 48 & was diagnosed with IDC, ER/PR + & HER-.
 Asked: 6/11/2015 If some one has an invasive tumor (.9mm in size) that is positive for estrogen, progesterone and HER2 protein overexpression (score 3)would chemo be advised?
 Asked: 6/11/2015 I have micro calcifications and 4 small (under 2 cm) tumors in my left breast.
 Asked: 6/11/2015 Is it normal for the GFR lab test to be low after chemotherapy? I have a gfr of 54 and my PCPs said it was low since last fall.
 Asked: 6/11/2015 How long can it be between a double mastectomy and chemotherapy? What is the standard time frame?
 Asked: 6/10/2015 My mother has Stage IIIc infiltrating ductal carcinoma ER + HER - with 29/30 + lymph nodes Had a lumpectomy done and axillary dissection 32 days...
 Asked: 6/10/2015 Age:67, Stage I (T1c N0 M0) invasive lobular, ER+/PR-, HER-2/neu 2+, FISH pending, Ki67 1%, E-cad negative, first lumpectomy to remove tumor, and second surgery...
 Asked: 6/6/2015 My mother is 80 years old. Relatively good health until she was diagnosed with breast cancer 5 weeks ago.
 Asked: 6/5/2015 I have IDC, node negative, oncotype 18, ER and PR + and Her- Tumor Stage 2A Would you recommend chemotherapy with this information? What is the...
 Asked: 6/5/2015 My Mom was diagnosed with invasive lobular cancer.
 Asked: 6/5/2015 Age 58. Stage 1 IDC (2.0) and DCIS, left breast.
 Asked: 6/5/2015 I''m 51 diagnosed with stage 2 multifocal invasive ductal carcinoma in the left breast.
 Asked: 6/3/2015 What are the current chemotherapeutic agents for IDC breast CA with 9 Axillary lymph nodes involved? considering patient already has Modified Radical Mastectomy. What should be...
 Asked: 6/3/2015 Stage II (T2 N0 M0) invasive lobular, grade 2, ER/PR negative, HER-2/neu negative, left breast.
 Asked: 6/3/2015 Age: 42. Diagnosed Feb 11, 2015 with a 1.1 cm, Stage 1, Grade 3, Oncotype 27 breast tumor with NO lymph node involvement.
 Asked: 5/31/2015 I was leaning towards not doing chemotherapy because my Oncotype score is 12.
 Asked: 5/31/2015 Have had one round of CMF and had few immediate side effects.
 Asked: 5/31/2015 I am 46. I had a bilateral mastectomy.
 Asked: 5/27/2015 Postmenopausal, IDC, 1.1cm, Stage 1, Grade 3, ER-positive 90%, PR-negative <1%, HER2-negative.
 Asked: 5/27/2015 Sorry to ask another question. Still not clear.
 Asked: 5/26/2015 Thanks so much for your help - it is much appreciated!! If I skip chemotherapy since my Oncotype score is 12, what about Tamoxifen resistance?..
 Asked: 5/26/2015 Thank you so much for your response.
 Asked: 5/26/2015 Mom diagnosed with IDC stage 2a, grade 2.
 Asked: 5/25/2015 My mom 62 years old is diagnosed with IDC stage 2a, grade 2. Tumor Size 4.0 cm, ER Positive, PR Negative, HER2- positive (3+) No...
 Asked: 5/25/2015 Thank you for answering my question. My doctors didn''t want to order the Oncotype DX for me.
 Asked: 5/23/2015 I was diagnosed with IDC 1.4 cm, stage 2a, grade 1, ER+ 96%, PR+ 94%, HER2-, 1 positive lymph node, KI67 6%.
 Asked: 5/21/2015 you state in 5/20 response that oncotype test is not valid in node positive , in earlier blogs you said it was valid which is it have things changed.
 Asked: 5/21/2015 I''ve gone through 4 rounds of TC for my Stage 2A 2.1cm BC with no lymph node involvement after a mastectomy without getting a second...
 Asked: 5/20/2015 a friend was prescribed chemo for dcis.
 Asked: 5/20/2015 I am 46 and was diagnosed with invasive lobular carcinoma with Grade 1, strong ER and PR sensitive, HER2 negative 1.5x1x1 cm.
 Asked: 5/20/2015 Had a rootcanal seriously troubling me for years before and around finding an estrogene lump of 1,6.
 Asked: 5/20/2015 I''m a woman, 46 yrs, had lump 1,6 cm removed 3 weeks ago.
 Asked: 5/19/2015 I have a grade 3 stage 2a cancer.
 Asked: 5/18/2015 I have estrogen positive invasive ductal carcinoma 1.3 cm in right breast and DCIS in left had double mastectomy with negative nodes.
 Asked: 5/17/2015 I was diagnosed with 7 liver mets - largest 2.0 cm in 2/2015 after 2 years of bone only and on Letrozole and then AA.
 Asked: 5/17/2015 I had a lumpectomy, 1.5 cm tumor estrogen positive, progesterone positive, HEr negative.
 Asked: 5/17/2015 Had lumpectomy for IDC 3.5 mm tumor.
 Asked: 5/16/2015 my 79 years old mother was diagnosis with invasive ductal mammary 2.5cm.
 Asked: 5/15/2015 I received an oncotype score of 14.
 Asked: 5/14/2015 I had IDC 1.5cm. Stage 1.
 Asked: 5/13/2015 I had a high grade, stage 2 invasive ductal ca removed 3weeks ago.
 Asked: 5/13/2015 Please advise if you would recommend chemo and hormone therapy or just homormone therapy? After a lumpectomy and interoperative radiation, I am currently receiving 3...
 Asked: 5/10/2015 IDC ER/PR pos. her2 neg.
 Asked: 5/10/2015 I''m waiting for the results of a Oncotype DX test before I decide if I am going to have Chemo in addition to Hormone...
 Asked: 5/10/2015 Hello, My mom, 71 years old, was diagnosed with Stage2A Invasive Duct Carcinoma.
 Asked: 5/8/2015 Hi I''m 40yrs old diagnosed with DCIS 7.5cm in size when final path reports came back it showed a 2.3mm metastatic carcinoma in 1/3 sentinel...
 Asked: 5/7/2015 I was diagnosed with breast cancer, stage 2 A, lesion 1.5 and one lymph node was cancerous.I had a lumpectomy.
 Asked: 5/5/2015 I was diagnosed with stage 2a breast cancer with t1, n1and m0 with 2/15 axillary lymph nodes involed and 03apical nodes with er weakly positive,...
 Asked: 5/5/2015 60 years old. Double mastectomy 3-31-2015.
 Asked: 5/3/2015 I was diagnosed with IDC 1.4 cm, stage 2a, grade 1, ER+ 96%, PR+ 94%, HER2-, 1 positive lymph node, KI67 6%, Oncotype DX 12.

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