Ask an Expert: Chemotherapy

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Questions about Neoadjuvant and Adjuvant Chemotherapy.
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 Asked: 11/12/2014 Is it normal to have elevated liver enzymes (ALT =47) after finishing chemo in April, rads in August of this year? Also, post chemo, I...
 Asked: 11/11/2014 What happens when your taxol is held for 3-4 weeks?? Due to a URI sounds ridulous but I think cancer should come first over holding...
 Asked: 11/10/2014 Are there any targeted chemo treatments for stage IIb, grade 3, Estrogen+,Progesterone +, HER2- breast cancer that can be used in a pre-menopausal women of...
 Asked: 11/10/2014 Follow-up to "59 , 1.5 cm...oncotype/chemo ques... Yes, know it''s personal but having a tough time deciding/understanding as I''m not sure if 4% is enough for...
 Asked: 11/10/2014 AM 59, 1.5CM IDC, stage 1b (microstat in sentinel node 1, not 2) grade 2, ER & PR+, Her-2neg, lumpectomy, oncotype score 27. My oncotype test...
 Asked: 11/9/2014 I am 60 yo women dx with IDC er+ pr+ stage 3a , 2.5cm tumor with 4 lymph nodes positive largest .9cm ( 1 just...
 Asked: 11/8/2014 My mom is 73 yrs old...her2+ and estrogen driven BC.
 Asked: 11/6/2014 DX with BID CA in August, stage 1 have undergone lumpectomy with sentinal node removal, report 1.3 CM moderately differienciated tumor, grade2, Estrogen Positive, Prog
 Asked: 11/6/2014 I am 30 years old Dx IDC (with small areas of DCIS within the tumor) 4cm, ER/PR positive, HER2 negative right breast.
 Asked: 11/6/2014 My sister had a breast biopsy last week and they diagnosed a 9 mm tumor as invasive ductal with micropapillary features.
 Asked: 11/5/2014 I am 36 years old, DX IDC, left breast, Stage I, multifocal, biggest focus had 0,6mm (total tumor area estimated in less than 1,5cm), Grade2,...
 Asked: 11/5/2014 It seems that OncotypeDx testing is trumping all other pathology markers.
 Asked: 11/5/2014 In a cancer diagnosis of breast cancer "Stage 3 double negative" what does the "double negative"mean?
 Asked: 11/4/2014 Follow-up to ques to response below re: 59 yr old CMF vs TC Are the side effects worse with TC and what can I expect? A little scared..
 Asked: 11/4/2014 Need help deciding between CMF & TC chemo tx Am 59, 1.5 cm IDC, stage 1b (micrometastisi in sentinel node 1, not 2..both removed), grade 2,...
 Asked: 11/4/2014 I am 61 years old, BRCA 2 mutation positive, Stage1 invasive ductal carcinoma, size 6mm, Her2 negative, Estrogen 100% positive, PR Alfred score 3:8,...
 Asked: 11/3/2014 I am 67 years old, ER+ & PR+, HER2-, 2 Class-1-positive tumors, double mastectomy on 7/29/14, positive lymph node + 1 removed.
 Asked: 11/2/2014 My ONCOdx test cited 1% benefit from chemo, so I decided not to do chemo.
 Asked: 11/2/2014 I have been diagnosed wiht breast cancer and have just undergone total mastectomy and sentinel node .
 Asked: 11/1/2014 Will an anthracycline and taxane based regime deliver any prognostic benefit other than achieved by amenorrhea? I''m pre-menopausal with a resected 20mm tumour, grade 3,...
 Asked: 10/31/2014 Hello, Does chemo always cause problems with the salivary glands even if they are not the focus of treatment? I''ve heard of people getting dry throats...
 Asked: 10/30/2014 I am age 56. Had left breast simple mastectomy (2.5cm invasive carcinoma) in May 2014.
 Asked: 10/29/2014 I have triple negative invasive ductal anenoid cystic breast cancer.
 Asked: 10/29/2014 I asked a previous question about being triple negative prior to mastectomy and PR positive after and you asked how positive is the PR? ...
 Asked: 10/29/2014 Before mastectomy the diagnosis was Triple negative per the breast biopsy but after mastectomy the pathology report states ER negative PR positive.
 Asked: 10/29/2014 Hello, I am 68, good health stage 11A invasive bc, onotype score 26, 15/13% risk range er 98% strong staining, pr 2% weak staining, negative fish...
 Asked: 10/29/2014 42, stage 1A, invasive ductal carcinoma, grade ll (intermediate), sentinel node negative, tumor size 0.9cm, ER positive, PR positive, HER-2 negative.
 Asked: 10/28/2014 Hello, my mum was diagnosed with breast cancer two weeks ago.
 Asked: 10/28/2014 I am trying to decide if I should get chemo therapy.
 Asked: 10/28/2014 Had a 9mm breast ca in left breast.
 Asked: 10/28/2014 Relative (42) just diagnosed with stage IIb, 2 cm, 1 lymph node (T1N1), ER+, PR+, equivocal HER2.
 Asked: 10/26/2014 If oncotype score is 19, are the percentages with/without chemo accurate? Mine are same 12 and 12, yet doctor recommends chemo If percentages are...
 Asked: 10/26/2014 Does JHU ever make a treatment decision based on mammaprint? How often? Why or why not?
 Asked: 10/26/2014 can I trust mammaprint low score with one positive node? Why would my doctor order this if she was not going to change decision based on...
 Asked: 10/25/2014 Oncotype score 19, mammaprint result low!! Tumor was 1.5 cm, ER + with 1 lymph node-positive. Both doctors recommend RXPonder trial for me where I have...
 Asked: 10/25/2014 have stage 1, grade 3, er-, pr+, 9mm left breast ca.
 Asked: 10/24/2014 I read many women/tumors don''t respond to Taxanes.
 Asked: 10/22/2014 Does duration of filgrastim matter very much? I have one onc telling me to start 1 day after infusion and administer for 3 or 4...
 Asked: 10/22/2014 My mother is 71 yrs and recently detected to have Ca breast MRM done with axillary clearance.
 Asked: 10/20/2014 51 year old. Had 9mm lump removed in July 2014.
 Asked: 10/19/2014 what is an academic breast center? Is Smillow at Yale an academic breast center? Are there any in CT? How can I find a list?
 Asked: 10/19/2014 I was diagnosed with IDC ER+PR-Her2+ grade 3, stage 1a no lymph nodes involved was in my right breast 1.3 cm, opted for double mastectomy...
 Asked: 10/19/2014 I was diagnosed with triple negative breast cancer in 2013.
 Asked: 10/16/2014 I was diagnosed with Stage 2, Grade 3, IDC 3.5 cm and was put on a neoadjuvant regimen every other week of 4 dose dense...
 Asked: 10/16/2014 I had Invasive ductal carcinoma, Nottingham grade III (of III) All margins negative for carcinoma.
 Asked: 10/16/2014 Hi my mum has just been diagnosed with IDC breast cancer, 2 different tumors, 1 in each breast.
 Asked: 10/16/2014 I have TNBC Stage IIA (T2N0). Neo-adjuvant therapy.
 Asked: 10/12/2014 58 invasive ductal carcinoma, 1.7 cm, one sentinal node positive, left mastectomy (breast was dense and fibrocyctic).
 Asked: 10/12/2014 Is there anything that I can do for the neuropathy from my chemo? It gets a little worse every couple of months.
 Asked: 10/10/2014 I had a bilateral mastectomy on sept 19 2014 from a triple negative breast cancer.
 Asked: 10/11/2014 I just finished my last treatment of taxol.
 Asked: 10/11/2014 What percent of women with Triple Negative Breast Cancer achieve a 100% Pathological Response, following neoadjuvant chemotherapy?
 Asked: 10/9/2014 I am 40 yrs old, stage 1 IDC, grade 2, nodes neg, ER+/PR+, HER-.
 Asked: 10/9/2014 Invasive ductal carcinoma left breast 1.8 cent ER+PR+HER- and right side DCIS with 5 mm HER+,ER- PR-,lymph nodes no disease on both sides, left has...
 Asked: 10/9/2014 I am 43 with 2.7 cm invasive ductal carcinoma.
 Asked: 10/8/2014 I have Triple Negative Breast Cancer and underwent neoadjuvant chemotherapy and surgery.
 Asked: 10/8/2014 For Triple Negative Breast Cancer, can a Pathologist determine the Pathological Complete Response if surgery is done before chemotherapy treatment? Also what percentage of women with...
 Asked: 10/7/2014 Is ill defined mass always cancer?
 Asked: 10/7/2014 Just got my surgical Pathological Report and was told I have 100 % PCR in my breast cancer - but the Pathological Report does not...
 Asked: 10/7/2014 Is it common though, for breast cancer surgery, in order to get clear margins to do the dissection down to the chest wall even...
 Asked: 10/6/2014 67 years. Grade 3 tumour.
 Asked: 10/6/2014 I have Triple Negative Breast Cancer. Already underwent neoadjuvant.
 Asked: 10/5/2014 Double mastectomy to remove 4.25 tumor and n right breast.
 Asked: 10/4/2014 I am 52 women. Last May surgery due to intra ductal ca Estrogens and progesterone +, Her negative.
 Asked: 10/3/2014 Does Chemo reduce my life span? 61 year old left breast stage 1, grade 1 cancer that is ER + PR - No lymph node cancer.
 Asked: 10/3/2014 I can eat chocolates even with Triple Negative Breast Cancer?
 Asked: 10/3/2014 I am 35 with no family history of breast dancer or any hormonal cancers.
 Asked: 10/3/2014 I have IDC, stage 2a, high grade, 2 tumours, 15mm and 5mm with DCIS.
 Asked: 10/3/2014 Is the oncotype test not considered accurate in a 7 cm tumor with 1 lymph node cancerous.
 Asked: 10/2/2014 57 yr old with Stage 1 IDC along with DCIS (both removed via lumpectomy with clear margins) that is triple positive HERC is 3+, no...
 Asked: 10/2/2014 Thanks for this excellent service! I was asking the MedOnc treating my mother about what to expect on chemo and what changes he would make...
 Asked: 10/2/2014 I am 52 yo, premenopausal, and was diagnosed with Invasive Ductal Carcinoma, Grade 2, stage 2b.
 Asked: 10/1/2014 Wife is 50, no children, menopausal Had stage 1 Insitu Ductal , clear borders, Not in Nodes, Did a Tissue saving mastectomy thought it would be over.
 Asked: 9/30/2014 I have Triple Negative Breast Cancer and Luv my chocolates.
 Asked: 9/30/2014 I have had a BMX on 8/27 for IDC stage 1 grade 3.
 Asked: 9/30/2014 I prevoiusly inquired about lymphedema fear. New diagnosis 9/18/14 IDC by sonogram guided core box, tumor 1.5cm, Grade 3, ER/PR - and HER2 - awaiting lumpectomy left breast with concurrent sentinel node biopsy.
 Asked: 9/29/2014 hi i have just been diagnosed with IDC ER 2/3+ POSITIVE IN MORE THAN 66% OF TUMOUR CELLS PR 1/2+ POSITIVE IN 50% OF TUMOUR CELLS HER-2 IHC...
 Asked: 9/29/2014 57yo with IDC in right breast, triple positive.
 Asked: 9/29/2014 Is it possible for me to be pregnant? I am 63.
 Asked: 9/27/2014 I completed chemo and surgery for Triple Negative Breast Cancer.
 Asked: 9/25/2014 I had an oncotype test wirth a score of 31if I do a double mastectomy would I still need chemo?
 Asked: 9/25/2014 Can you please explain the phrase..benefit from Chemo? Am i correct in thinking it means risk vs.
 Asked: 9/24/2014 43 yr old .7cm IDC, stage 1, Grade 2, ER/PR positive, Her2 equivocal on IHC, negative on FISH, node negative, had double mastectomy, skin/nipple sparing
 Asked: 9/23/2014 Then how long after the final infusion does the chemo work on the body? I completed.
 Asked: 9/23/2014 I had mastectomy 9-15-14 for breast cancer on both sides - estrogen positive and I am premenuposal.
 Asked: 9/23/2014 I have ILC ( 3.8 cm removed )left masectomy.
 Asked: 9/23/2014 I completed chemo (AC and Taxol - 4 rounds each), on Aug 15.
 Asked: 9/22/2014 I finished chemotherapy for Triple Negative Breast Cancer on August 15 and had surgery on Sept 17.
 Asked: 9/21/2014 my wife is having left breast cancer.
 Asked: 9/14/2014 What is your standard chemo treatment for: 1.9 cm IDC E+P+ her - multifocal with several 5cm -...
 Asked: 9/13/2014 I have had three round of CT chemo, and I want to know the risk if I choose not to do round 4 and move to rads.
 Asked: 9/13/2014 Is a yearly mammogram necessary at age 76? My wife has had a steriotactic biopsy 5 years ago which was negative..
 Asked: 9/10/2014 I have sclerotic bone mets which seem to be stable.
 Asked: 9/8/2014 I am a 47 yr old who recently underwent mastectomy for breast cancer.
 Asked: 9/8/2014 My 43 year old daughter had Bilateral Mastectomies, 2 weeks ago, today. Final Diagnosis Right breast & Axillary lymph nodes (Modified Radical Mastectomy): -Invasive ductal carcinoma, Grade 2...
 Asked: 9/8/2014 I had a total mastectomy on my left breast.
 Asked: 9/7/2014 I have progesterone and estrogen positive 1.2 cm tumor with ( invasive ductal carcinoma) plus 2 small tubular cancers (3mm and 4mm) found...
 Asked: 9/7/2014 Thank you for your prompt response to my question.
 Asked: 9/6/2014 My 47 year old daughter was diangosed with a 7 mm infiltrating ductal carcinoma ER+ PR+ HER2 - ki67 40.
 Asked: 9/6/2014 My last chemo infusion for Triple Negative Breast Cancer was on August 15/14.

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