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Understanding Pathology Results
Questions explaining and understanding pathology results.
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 Asked: 2/18/2017 I was diagnosed with fibrocystic change with nodular pseudoangiomatous stromal hyperplasia, cysts, apocrine metaplasia, adenosis, stromal fibrosis and microcalcifications in benign ducts and stroma
 Asked: 2/18/2017 I had a question about onoctype. Say someone has a 1cm tumor with negative nodes versus a 4.5cm tumor with negative nodes and they both had the same onoctype score.
 Asked: 2/18/2017 Thank you so much for yr answer to my question i just posted (tnbc 1,2 cm).
 Asked: 2/17/2017 Hi. Was diagnosed april 2016 tnbc 1,2cm 0/16 nodes ki67 50% grade 3.
 Asked: 2/15/2017 I''m 52 Diagnosed Nov 1st 2016 Left breast multi-focal IDC 3.5cm grade 2 ER85% PR8% KI67 18% 3/5 nodes positive on path Stage 2B Dec...
 Asked: 2/13/2017 Hi Lillie! There are so many scary things out there about Luminal B breast cancer.
 Asked: 2/11/2017 ER positive 90% strong intensity nuclear staining, PR positive 90% strong intensity nuclear staining, HER 2 negative (0 and focal 1+ staining , Ki-67 12%...
 Asked: 2/8/2017 What does Moderately-differentiated invasive ductal carcinoma with minimal stromal fibrosis mean?
 Asked: 2/8/2017 Hi Lillie and many thanks for all your help.
 Asked: 2/6/2017 I was diagnosed with ER+, PR-, Her2-,tiny 5mm tumor.
 Asked: 2/6/2017 My pathologic staging of colorectal cancer says pT2NoMx, please advise which stage is this and what are the survival..
 Asked: 2/5/2017 Trying to understand what biopsy report means.
 Asked: 2/5/2017 My wife was diagnosed with breast cancer in 2013.
 Asked: 2/4/2017 My biopsy report says P40 immunostains are positive.
 Asked: 2/4/2017 Is a diagnosis DCIS, Nuclear Grade 3of 3, with solid and comedo architectural patterns.
 Asked: 2/3/2017 My pathology report says I have DCIS, Nuclear Grade 3of 3, with solid, cribriform, and comedo architectural patterns.
 Asked: 2/2/2017 Any follow up needed for core breast biopsy for results of (1)enlarged lobular units with columnar alteration and mild usual type epithelial hyperplasia (2) calcifications...
 Asked: 2/1/2017 I had a stereotactic biopsy and it came back with fibrocystic change with nodular pseudoangiomatous stromal hyperplasia, among other things.
 Asked: 2/1/2017 my mammogram read small mass in the upper posterior right breast is stable and appears to be a lymph node.
 Asked: 1/30/2017 Is there a difference in a sentinel node being positive and a lymph node being positive for cancer??
 Asked: 1/30/2017 I am confused with the results and wondering if someone could help me understand the pathology report.
 Asked: 1/29/2017 Does Nottingham score of 6( with mitotic grade of 1, er+, pr-, her2 neg, ki67 of 60, 2.2 cm, no node involvement, lvi identified.
 Asked: 1/28/2017 At time of biopsy my ki67 was 35 on 12/7.
 Asked: 1/28/2017 Does a ki67, of 60, mitoic grade 1, 2.2cm, with lvi mean chemo is necessary.
 Asked: 1/27/2017 Does a ki67 percentage of 60 outweigh a multicultural grade of one and thus throw the oncotypedx result into the high risk category?
 Asked: 1/27/2017 I have been diagnosed with stage 2a idc.
 Asked: 1/27/2017 I had by stereotactic biopsy completed, but am still concerned.
 Asked: 1/26/2017 Can someone explain this please? I can find the definition of "usual" & "atypical" but this seems to be a combo? Any help is greatly...
 Asked: 1/26/2017 My mother was diagnosed with a breast cancer and subjected to the surgery.before the surgery the ultra sound scan indicated two enlarged lymph nodes.but in...
 Asked: 1/19/2017 biopsy report: detached fragments of markedly atypical cells, highly suspicious for carcinoma.
 Asked: 1/18/2017 5/17/16 had partial mx for widespread dcis left breast (no mass nothing palpable saw on mammo and MRI).
 Asked: 1/11/2017 I have IDC stage 1A breast cancer. Had lumpectomy on Dec 2016, the pathology report said: FOCI SUSPICIOUS FOR LYMPHOVASCULAR INVASION. After lumpectomy I had sentinel surgery, found...
 Asked: 1/10/2017 My biopsy reports contains the following: Apocrine metaplasia with mild atypic (See Note). Micropapilloma Micro calcifications are identified in the apocrine areas as well as the micropapilloma. NOTE: extensive...
 Asked: 1/7/2017 In the following path report below, am I correct in understanding the nottingham score to be as follows: Mitotic rate: 1-10 per 10 /hpf...
 Asked: 1/3/2017 Hi, 8 gauge vac stereotactic biopsy found DCIS high grade with comedo necrosis, microcalcs, ER+/PR+, no invasive cells in the sample.
 Asked: 1/3/2017 Just recently received my pathology report from lumpectomy due to high grade DCIS ER/PR neg 7cm.
 Asked: 1/2/2017 Please tell me what this means as it relates to treatment options: A. Right breast, 11o''clock N+3, needle core biopsy (slides A 1x3 and six fmmunohistochemical stain...
 Asked: 1/1/2017 Hi, I was diagnosed with ALH, and of course it said that the E-cahedrin (I think I spelled it right) was negative or gone (I''m...
 Asked: 12/29/2016 Hello.. I am 28 years old and currently breastfeeding my 2nd child.
 Asked: 12/29/2016 To whom it may concern, I did the laboratory test for ANA.
 Asked: 12/28/2016 Sterotactic biopsy R breast 6:00 report states:Sections show high grade DCIS with apocrine features and central necrosis.
 Asked: 12/26/2016 After surgery, a 43 years female patient has the followings in her histopathology and immunocyto-histochemistry reports for breast cancer: Grade 2 : Scored as 6 (Nottingham...
 Asked: 12/21/2016 What does lymphovascular space invasion:focally present in breast cancer.
 Asked: 12/20/2016 Diagnosed w/ bilateral synchronous BC 2 years ago.
 Asked: 12/14/2016 WHat does it mean when an oncologist referrs to a cancer as Luminal B? I know its a general term but I am not sure what it is indicative of..
 Asked: 12/14/2016 I apologize I asked a question and left out this info: I am ER+ PR+ Her2- OncoDX 20.
 Asked: 12/14/2016 I have not really understood what the following path report is telling me.
 Asked: 12/13/2016 I was just diagnosed with left breast 12: o''clock apocrine carcinoma invasive (0.2cm) and in-istu high grade nuclear.
 Asked: 12/11/2016 I had a mastectomy and they found I had stage IIA invasive breast cancer, ER+, PR+, Her2-, grade 2, MITOSIS rate 10.
 Asked: 12/8/2016 My core needle biopsy report describes a small portion of hyperplastic ducts with a cribriform architecture.
 Asked: 12/5/2016 Hello, I just submitted a question regarding tnbc stage 2 diagnosis and pathology report. I failed to mention that a sentinel node biopsy was performed and...
 Asked: 12/5/2016 Hello, I was diagnosed with tnbc stage 2b in April.
 Asked: 12/4/2016 casting calcifications on 6.5 cm area. stereotactic biopsy diagnosis shows DCIS, cribiform and micropapillary with patterns of necrosis and multiple associated microcalcifications, grade 2 with microinvasion seen.
 Asked: 12/3/2016 What''s the treatment for situ carcinoma involving multiple core fragments?
 Asked: 12/2/2016 Right true vocal cord biopsy: Hyperplastic squamous mucosa with focal mild dysplasia. Marked cautery artifacts seen. No evidence of malignancy. TNM
 Asked: 11/30/2016 Hi i was just wondering about oncotype both 15 and 20 being intermediate as you said on the previous post..
 Asked: 11/29/2016 Would you rather have an oncotype score of 15 with one positive node or a score of 20 with negative nodes? .
 Asked: 11/29/2016 Thank you for answering my previous question.
 Asked: 11/28/2016 what does Moderately differentiated invasive ductal carcinoma (tubule formation 3/3, nuclear pleomorphism 2/3, mitotic counts 1/3) measuring 0.4cm in maximal length and intralymphatic tumor...
 Asked: 11/27/2016 My mother is diagnosed with DCIS.her pathology reports says she is immunopositive for HER2/neu.what does it mean?is it good thing or something to worry about.her...
 Asked: 11/27/2016 hi Lillie, thank you so much for your previous responses.
 Asked: 11/25/2016 I was not sure what category to put this in.
 Asked: 11/22/2016 I had breast cancer two years ago (stage 1A, not in lymph nodes, had lumpectomy, 4 rounds of chemo and radiation).
 Asked: 11/22/2016 I''m 40 years old with no past pregnancies.
 Asked: 11/21/2016 My biopsy diagnosis says Invasive Lobular Carcinoma, 0.2 cm maximum dimension, grade 6/9 on the Nottingham scale.
 Asked: 11/21/2016 I had a single masectomy on right breast Nov 11th.
 Asked: 11/21/2016 I recently had a mammogram and ultrasound that were BiRad 5.
 Asked: 11/17/2016 My stereotactic needle core biopsy report stated "duct carcinoma in site, micro-papillary and cribriform type, intermediate nuclear grade, without necrosis"
 Asked: 11/16/2016 I was recently diagnosed at 52 with IDC grade 2 with micropapillary features, multifocal three tumors largest 19mm lumpectomy in December at Emory then rads
 Asked: 11/15/2016 My mother is 58 and her biopsy results says" left nipple has paget and large lactiferous duct shows evidence of cancerisation.what does it mean? Is...
 Asked: 11/15/2016 I am writing this for mother she is 58,In her biopsy report left nipple is dignosed as paget some features of cancerisation in lactiferous duct.what...
 Asked: 11/14/2016 I had an HER2+ tumor, which was Grade 2 (tubule formation 3+, nuclear pleomorphism 3+, mitotic index 1+ =7.
 Asked: 11/12/2016 Breast path is mucinous and lymph node is metastatic poorly differentiated mammary ducal carcinoma with necrosis.
 Asked: 11/11/2016 my results from ultrasound breast biopsy-were fragments of benign breast tissue with ill defined areas of dense nonspecific stromal fibrosis and a minute focus of...
 Asked: 11/9/2016 CNB in voluminous zone attenuation in area wide 34 mm, CNB:attached and fatty breast stroma with infiltrated invasive lobular breast carcinoma (E-cadherin negative tumor cells)in...
 Asked: 11/7/2016 I am reading how ki-67 is not a completely reliable measure of proliferation because of a "lack of standard methodology and type of antibody used...
 Asked: 11/7/2016 My fine needle biopsy report showed a 1 cm tumor with apocrine features and nuclear grade 3, no ER, PR, or HER2 testing was done.
 Asked: 11/6/2016 *4.0cm tumor, found less than 1 year after prior year’s clean mammogram, right breast *Core needle biopsy-Pathology report diagnosis- invasive and in situ ductal carcinoma ...
 Asked: 11/6/2016 My pathology report indicates I have invasive ductal carcinoma with apocrine and micropapillary features and abundant necrosis.
 Asked: 11/6/2016 I''m a 2 year triple negative breast cancer survivor.
 Asked: 11/6/2016 Hello, I asked a previous question before receiving my pathology report.
 Asked: 11/3/2016 Can a bone infarct in the area of the humerus bone evolve and/or move ? And what does this show up in an X-ray as?
 Asked: 11/1/2016 Please explain the following on my daughter''s breast ultrasound: There is a complex lesion at the 12-00 position measuring 6 mm showing internal echoes...
 Asked: 11/1/2016 Can you give me an interpretation of the following: There is a hypoechoic nodule measuring at 6 x 5 x 6 mm.
 Asked: 10/31/2016 Writing for my 45 year old daughter.
 Asked: 10/30/2016 My first cancer was IDC 6mm,markedly pleomorphic nucleus gr 2,er pos 90%, pr pos 5%, her2 neg.
 Asked: 10/30/2016 Hi, are bone scans accurate in determining metastatic breast cancer?
 Asked: 10/30/2016 BI-RADS 5, 2x US guided FNA. Cithological result 1: in all samples a considerable amount of fat tissue, abundant basophil substance, extracellular fat.
 Asked: 10/28/2016 Can you tell me what this means and what my score is? Average HER2 GENE copies/cell: 5.3 Average CEP17 signal/cell:2.62 HER2:CEP17 ratio:2.08 Comments:...
 Asked: 10/27/2016 When there is a benign breast tissue with focal stromal sclerosis and focal microcalcifications, what does it mean? Is the focal stromal sclerosis and microcalcifications...
 Asked: 10/25/2016 IDC Stage 1, 6mm, grade 2, 99% er/pr+, HER- with one out of two lymph nodes having a .2mm micromet.
 Asked: 10/25/2016 My mother''s report says: ER -(3/8) Positive. PR -(3/8) Positive. Her2 neu -Positive. Ki67 -30% MRM done 3 weeks back.
 Asked: 10/24/2016 If my pathology report says "Infiltrating Ductal Carcinoma with Micropapillary features," is that the same as Invasive Micropapillary Carcinoma of breast (IMPC) which I read...
 Asked: 10/23/2016 I was diagnosed with 4 cm. high grade comedo DCIS.
 Asked: 10/23/2016 How well will chemo work on a grade 1 tumor with a miotic rate of 2? Thank you! .
 Asked: 10/23/2016 What is the scale for miotic count regarding the Nottingham scale? I''ve seen varying scales.
 Asked: 10/23/2016 I am IDC stage 1a, grade 1, 6mm tumor.
 Asked: 10/23/2016 Hi Lillie, Thank you for answering my questions.
 Asked: 10/21/2016 Could you please put this in perspective for me? Is it more favorable to have a stage 1a breast tumor with an onco score...
 Asked: 10/18/2016 Thanks for your reply. Perhaps my question wasn’t clear – I asked about a tiny dcis – the definitive pathology after nipple excision called it intermediate grade dcis, clean margins, 2 mm, solid, no necrosis.

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