Ask an Expert: Understanding Pathology Results

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Understanding Pathology Results
Questions explaining and understanding pathology results.
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 Asked: 12/27/2014 "Invasive carcinoma, favor pleomorphic lobular, histologic grade 3 and nuclear grade 3." What does it mean??pls help.I''m worried abt my mom!
 Asked: 12/26/2014 What does positive 1+ staining in 2-3% of nuclei and negative 1+ staining in less than 1% of nuclei mean?
 Asked: 12/24/2014 I have a biopsy report which says Ductal carcinoma in-situ grade II with few foci suspicious of invasion My doctor wants to do a lumpectomy and a...
 Asked: 12/23/2014 Thank you for answering my previous question regarding the mucinous cancer.
 Asked: 12/22/2014 My HER2 status came back equivocal on IHC and FISH.
 Asked: 12/22/2014 First off'' I want to thank you for what you do.
 Asked: 12/22/2014 I was diagnosed with right breast Stage 1 Grade 2 T1b (9mm) N0 (0/) M0 invasive micropappilary cancer with lymphovascular invasion and Grade 2 DCIS.
 Asked: 12/21/2014 I was dx. with IDC, Stage II, grade 2 via core biopsy.
 Asked: 12/21/2014 I have read where if you have micropapillary patterns present in your invasive ductal carcinoma that recurrence rates are high even if mastectomy was done
 Asked: 12/19/2014 I was diagnosed with intraductal papillomata with calcifications and intraductal papilloma with rare calcifications.
 Asked: 12/18/2014 I was diagnosed with a complex sclerosing lesion with micro calcifications measuring 22mmx16mmx13mm after MRI guided core needle biopsy on 12/10.
 Asked: 12/16/2014 Follow up to your reply on 12/15.
 Asked: 12/15/2014 I have been diagnosed with 1cm cancer ER+, PR weakly positive, HER 2 negative and Ki- 67 58%. Original recommended treatment was lumpectomy, radiation, anti hormonal...
 Asked: 12/15/2014 I had an ultrasound-guided core needle biopsy performed a week ago.
 Asked: 12/15/2014 Hello I got my biopsy back The doctor said I had microcalcifications.
 Asked: 12/12/2014 Microscopic examination of a FNA indicated: 1) A few papillary structures.
 Asked: 12/12/2014 Results from second surgery to clear one margin: "No residual invasive carcinoma is identified.
 Asked: 12/11/2014 My Wife had an aspiration performed which resulted in the following description: - "a few Papillary structures - "large clusters of epithelial cells" - "coarse chromatin" - "Some nuclei...
 Asked: 12/8/2014 My core needle biopsy just say''s Proliferative Fibrocystic Changes that''s it.
 Asked: 12/7/2014 Just revisiting the question I asked a couple days ago.
 Asked: 12/6/2014 I''m very concerned that LVI was found on one slide.
 Asked: 12/6/2014 I am 59 years old. My ki67 score is 7% (low) and mitotic rate was a 1.
 Asked: 12/6/2014 Another poster says that Oncotype DX does not work on LVI? Is that true? In another post you said the test is used on node positive patients.
 Asked: 12/6/2014 Hi, I am just beginning what feels like an already long process of being diagnosed.
 Asked: 12/5/2014 Hi Lillie.
 Asked: 12/4/2014 I wrote the following last night: " I am revisiting a question I posted last week.
 Asked: 12/4/2014 I am revisiting a question I posted last week.
 Asked: 12/3/2014 The results from my biopsy (as read to me over the phone) came back as DCIS, nuclear grade 2-3 cribriform and solid pattern with focal...
 Asked: 12/3/2014 Core biopsy done and no hx of mastitis no trauma or injury to area path report says acute chronic mastitis and fat necrosis ...
 Asked: 12/2/2014 My doctor performed an ultrasound on two lumps which led to a needle biopsy on both.
 Asked: 11/26/2014 I was diagnosed with ILC of my left breast in September.
 Asked: 11/26/2014 I had two biopsies done on two separate lesions on my right breast that were ER+.
 Asked: 11/24/2014 I have 5 pgs of babble but mostly want to know what my odds for survival are and what if any chemo you would recommend...
 Asked: 11/25/2014 I have been told that my breast cancer was high in ki-67 (40).
 Asked: 11/24/2014 hi there.
 Asked: 11/24/2014 Sorry about that. In addition to my first question I am Her2 negative, estrogen & progesterone positive.
 Asked: 11/23/2014 I have 5 pgs of babble but mostly want to know what my odds for survival are and what if any chemo you would recommend...
 Asked: 11/20/2014 Hello, I''m hoping to get help with understanding the stage and prognosis I''m facing based on the following lumpectomy proctology report.
 Asked: 11/20/2014 I am a 53 year old woman considered to be peri-menopausaI.I was diagnosed with DCIS (Sept.
 Asked: 11/20/2014 What does the following diagnosis (both from the same biopsy) mean? 1.Invasive ductal carcinoma with focal necrosis 2.Ductal carcinoma in situ, intermediate nuclear grade, solid and cribriform...
 Asked: 11/19/2014 My ultrasound-guided needle biopsy came back benign, but my surgeon thinks there is a 70% chance it is a carcinoma.
 Asked: 11/18/2014 Following a biopsy of breast please explain the following: the MIB (K-67) report shows - 18% Intermediate / HER-2 (2+) Equivocal .
 Asked: 11/18/2014 "In the lateral aspect of the breast, along the deep margin there is another very hard, highly suspicious nodule which measures 20x10x5mm and this nodule...
 Asked: 11/17/2014 What does it mean on path report when it says tumor 5.
 Asked: 11/17/2014 My report shows tubules 3/3 pleomorphism 2/3 mitotic rate 1/3.
 Asked: 11/17/2014 are positive S100, CD68 and negative pankeratin enough to r/o malignancy in a granulomatous breast tissue involving dermis (nipple)? I thought differential dx for...
 Asked: 11/13/2014 Wow, what a great web site. I just got the pathology report from my DCIS surgery.
 Asked: 11/12/2014 1. If you have had a double mastectomy can you still have radiation 2.
 Asked: 11/11/2014 i had a biopsy and dr tells me it''s benign.
 Asked: 11/11/2014 I have HERS negative, stage 1b, invasive ductal carcinoma with a SBR grade: histolgic grade = 2 nuclear grade = 2 Mitosis score = 1 what does...
 Asked: 11/11/2014 what is the difference between stage 1A and 1B please.
 Asked: 11/6/2014 Hello- perhaps you can help me understand this report: tumor size 6 cm, left breast invasive ductal carcinoma, left axillary lymph node collection of poorly differentiated...
 Asked: 11/5/2014 I should begin this with I don''t feel anything.
 Asked: 10/31/2014 Part of the results also said, I''m not sure what this means.
 Asked: 10/30/2014 Hi there. I had a biopsy at the beginning of treatment and the report came back triple negative 0% staining on ER+ PR+.
 Asked: 10/30/2014 I''m so sorry for all the questions.
 Asked: 10/30/2014 So maybe I don''t need chemo then since it hasn''t broken thru on its own.
 Asked: 10/29/2014 Thanks so much. Forgot to put dr side the invasive cells had not gotten thru the duct walls yet.
 Asked: 10/29/2014 When I was diagnosed with er+ stage 3 breast cancer last year, it was described as very aggressive because it was grade 3.
 Asked: 10/29/2014 I''ve been diagnosed dcis with invasive components.
 Asked: 10/28/2014 My recent mastectomy path report shows invasive carcinoma, pT1c, recurrent near the original site, grade G2, moderately differentiated, clean margins, ER/HR positive HER2 equivocal, pNX...
 Asked: 10/26/2014 Hello! Im diagnost with idc, er, pr+ anf her2 negative.
 Asked: 10/25/2014 I had suspected breast granuloma excision and pathology tested for S100 and CD68 and karoten.
 Asked: 10/25/2014 Diagnosis: Infiltrating ductal carcinoma, poorly differentiated. Microscopic findings: consists of dense fibrous tissue infiltrated by nests and cords of tumor cells showing avoid and polygonal hyperchromatic nuclei For now, this are the only information I know because I don''t have a copy of the pathology results. What stage is this? My mother had mastectomy (not sure what type because we haven''t talked since she was brought to the hospital) a few days ago and we were to be referred to an Oncologist for possible chemo or other treatments 2 weeks from now.
 Asked: 10/22/2014 Invasive ductal carcinoma in situ solid type grade 2/3.
 Asked: 10/22/2014 My surgeon and oncologist both told me that I had a complete response, which was earlier seen by MRI and confirmed at surgery, with no...
 Asked: 10/22/2014 I have a very strong family history of BC and have been tested for BRCA which we do not have in the family.
 Asked: 10/22/2014 I had 1.2 cm, grade 2, no nodes involved.
 Asked: 10/19/2014 My excisional biopsy pathology report stated that I had high grade DCIS with lobular cancerization and the margins of biopsy were not clear.
 Asked: 10/19/2014 What does "Focal dilation in left breast- birads 2" means ?
 Asked: 10/15/2014 My diagnosis indicates papillary DCIS and my oncologist states it is not cancer.
 Asked: 10/14/2014 initial biopsy results: nottingham grage 6/9, tubules 3/3, nuclear grade 2/3, mitoses 1/3, tumor size 1.3 cm, ER positive 100%, PR postive 98%, HER-2/neu negative,...
 Asked: 10/12/2014 In addition to the actual 15 mm IDC discovered, mastectomy pathology stated the following: Atypical ductal hyperplasia Epithelial hyperplasia with atypia Rare microcalcifications throughout entire breast Because I was...
 Asked: 10/12/2014 Invasive ductal carcinoma, papillary type, Nottingham grade II, 0.5 cm in greatest dimension, involving both cores.
 Asked: 10/10/2014 I have been diagnosed with Invasive Ductal Carcinoma, High Grade (Nottingham Score 9/9) What stage of breast cancer is that?
 Asked: 10/11/2014 My pathology report after breast biopsy read: sections reveal an aggregate of acini.
 Asked: 10/8/2014 I had a lumpectomy. Please clarify what this means - is it good news or bad news? Do findings increase my risk of recurrence? 1.
 Asked: 10/5/2014 Had lymph nodes removed with first breast ca dx in 1997 (DCIS, tubular carcinoma treated w/ lumpectomy and radiation).
 Asked: 10/5/2014 After several years of repeat mammograms& callbacks for additional views followed by ultrasound on 2 of those occasion- for density changes and asymmetry (that didn''t...
 Asked: 10/5/2014 My pathology on removed breast states resiudal 2.5 x 1.3cm.
 Asked: 10/1/2014 I had a lumpectomy/sentinel node biopsy after 34 days of Letrozele Invasive breast cancer diagnosis tumor 1.5x1.2 with overall tumor cellularity/ clean margins 2 lymph node #1, level...
 Asked: 10/1/2014 My pathology report is as follows: Rt.
 Asked: 9/29/2014 I just submitted a question and misspelled so many words.
 Asked: 9/29/2014 June 30th two punch biopsies read: A.
 Asked: 9/26/2014 newly dx with invasive ductal carcinoma - initial biopsy results: nottingham grage 6/9, tubules 3/3, nuclear grade 2/3, mitoses 1/3, tumor size 1.3 cm, ER...
 Asked: 9/26/2014 My pathology report states right sentinel #1 isolated rumor cells (ITCs) identified within one of 3 lymph nodes.(Immunohistochemical stain for pancytokeratin is positive within...
 Asked: 9/26/2014 could you pls tell me what ductal carcinoma in situ with comedonecrosis and epithelial calcifications, tumor size 0.1 cm greatest tumor dimension means? this result...
 Asked: 9/25/2014 How abnormal is it to have numerous cycts in both breast and also in the armpits ? Left:10 Right: 7 Please advise, thank you..
 Asked: 9/24/2014 i would like to know the grading of non-Hodgkin Lymphomas and the basis of the grading please, Thanks .
 Asked: 9/23/2014 My pathology report (ultrasound guided core biopsy) says: "Sclerosing lesion with usual ductal hyperplasia, columnar cell change and calcifications. Immmunohistochemical stains for CAM 5.2, p63 and smooth...
 Asked: 9/23/2014 My Mom''s pathology report is as stated: Invasive Ductal Carcinoma.
 Asked: 9/22/2014 My question: What does the below pathology report mean [in laymans terms? ] Also, is an excisional biopsy the same thing as a...
 Asked: 9/21/2014 I had a sterotactic core biopsy and the diagnosis was Fibrofatty breast tissue with focal minimal incidental atypical lobular hyperplasia.
 Asked: 9/15/2014 I had a sterotactic biopsy. No malignancy found, but because there''s "rare foci of flat epithelial atypia", doctor is recommending more invasive surgical biopsy.
 Asked: 9/15/2014 I was dignosed with invasive ductal carcinoma from a needle biopsy the after mastectomy with no treatment pathology report said no residual tumor and the...
 Asked: 9/15/2014 The National Comprehensive Cancer Network Guidelines dictates that a woman with a breast cancer tumor more than 1 cm regardless of onco score should have...
 Asked: 9/15/2014 I just had lumpectomy which revealed dcis high grade focally extending to within 1 mm of closest surgical margin.
 Asked: 9/14/2014 My pathology report states DCIS pTis 12 mm DCIS noted in three separate tissue blocks, solid grade 3 focal non expansive central necrosis.
 Asked: 9/14/2014 Hello,, what does it mean in simple terms when pathology reports reads, infiltrating ductal carcinoma of no special type??
 Asked: 9/12/2014 Hi there: I have been diagnosed with 2 biopsies to have an adenosis tumor and a hamartoma in the 2nd biopsy.

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