Ask an Expert: Understanding Pathology Results

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Understanding Pathology Results
Questions explaining and understanding pathology results.
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 Asked: 11/20/2014 Hello, I''m hoping to get help with understanding the stage and prognosis I''m facing based on the following lumpectomy proctology report.
 Asked: 11/20/2014 I am a 53 year old woman considered to be peri-menopausaI.I was diagnosed with DCIS (Sept.
 Asked: 11/20/2014 What does the following diagnosis (both from the same biopsy) mean? 1.Invasive ductal carcinoma with focal necrosis 2.Ductal carcinoma in situ, intermediate nuclear grade, solid and cribriform...
 Asked: 11/19/2014 My ultrasound-guided needle biopsy came back benign, but my surgeon thinks there is a 70% chance it is a carcinoma.
 Asked: 11/18/2014 Following a biopsy of breast please explain the following: the MIB (K-67) report shows - 18% Intermediate / HER-2 (2+) Equivocal .
 Asked: 11/18/2014 "In the lateral aspect of the breast, along the deep margin there is another very hard, highly suspicious nodule which measures 20x10x5mm and this nodule...
 Asked: 11/17/2014 What does it mean on path report when it says tumor 5.
 Asked: 11/17/2014 My report shows tubules 3/3 pleomorphism 2/3 mitotic rate 1/3.
 Asked: 11/17/2014 are positive S100, CD68 and negative pankeratin enough to r/o malignancy in a granulomatous breast tissue involving dermis (nipple)? I thought differential dx for...
 Asked: 11/13/2014 Wow, what a great web site. I just got the pathology report from my DCIS surgery.
 Asked: 11/12/2014 1. If you have had a double mastectomy can you still have radiation 2.
 Asked: 11/11/2014 i had a biopsy and dr tells me it''s benign.
 Asked: 11/11/2014 I have HERS negative, stage 1b, invasive ductal carcinoma with a SBR grade: histolgic grade = 2 nuclear grade = 2 Mitosis score = 1 what does...
 Asked: 11/11/2014 what is the difference between stage 1A and 1B please.
 Asked: 11/6/2014 Hello- perhaps you can help me understand this report: tumor size 6 cm, left breast invasive ductal carcinoma, left axillary lymph node collection of poorly differentiated...
 Asked: 11/5/2014 I should begin this with I don''t feel anything.
 Asked: 10/31/2014 Part of the results also said, I''m not sure what this means.
 Asked: 10/30/2014 Hi there. I had a biopsy at the beginning of treatment and the report came back triple negative 0% staining on ER+ PR+.
 Asked: 10/30/2014 I''m so sorry for all the questions.
 Asked: 10/30/2014 So maybe I don''t need chemo then since it hasn''t broken thru on its own.
 Asked: 10/29/2014 Thanks so much. Forgot to put dr side the invasive cells had not gotten thru the duct walls yet.
 Asked: 10/29/2014 When I was diagnosed with er+ stage 3 breast cancer last year, it was described as very aggressive because it was grade 3.
 Asked: 10/29/2014 I''ve been diagnosed dcis with invasive components.
 Asked: 10/28/2014 My recent mastectomy path report shows invasive carcinoma, pT1c, recurrent near the original site, grade G2, moderately differentiated, clean margins, ER/HR positive HER2 equivocal, pNX...
 Asked: 10/26/2014 Hello! Im diagnost with idc, er, pr+ anf her2 negative.
 Asked: 10/25/2014 I had suspected breast granuloma excision and pathology tested for S100 and CD68 and karoten.
 Asked: 10/25/2014 Diagnosis: Infiltrating ductal carcinoma, poorly differentiated. Microscopic findings: consists of dense fibrous tissue infiltrated by nests and cords of tumor cells showing avoid and polygonal hyperchromatic nuclei For now, this are the only information I know because I don''t have a copy of the pathology results. What stage is this? My mother had mastectomy (not sure what type because we haven''t talked since she was brought to the hospital) a few days ago and we were to be referred to an Oncologist for possible chemo or other treatments 2 weeks from now.
 Asked: 10/22/2014 Invasive ductal carcinoma in situ solid type grade 2/3.
 Asked: 10/22/2014 My surgeon and oncologist both told me that I had a complete response, which was earlier seen by MRI and confirmed at surgery, with no...
 Asked: 10/22/2014 I have a very strong family history of BC and have been tested for BRCA which we do not have in the family.
 Asked: 10/22/2014 I had 1.2 cm, grade 2, no nodes involved.
 Asked: 10/19/2014 My excisional biopsy pathology report stated that I had high grade DCIS with lobular cancerization and the margins of biopsy were not clear.
 Asked: 10/19/2014 What does "Focal dilation in left breast- birads 2" means ?
 Asked: 10/15/2014 My diagnosis indicates papillary DCIS and my oncologist states it is not cancer.
 Asked: 10/14/2014 initial biopsy results: nottingham grage 6/9, tubules 3/3, nuclear grade 2/3, mitoses 1/3, tumor size 1.3 cm, ER positive 100%, PR postive 98%, HER-2/neu negative,...
 Asked: 10/12/2014 In addition to the actual 15 mm IDC discovered, mastectomy pathology stated the following: Atypical ductal hyperplasia Epithelial hyperplasia with atypia Rare microcalcifications throughout entire breast Because I was...
 Asked: 10/12/2014 Invasive ductal carcinoma, papillary type, Nottingham grade II, 0.5 cm in greatest dimension, involving both cores.
 Asked: 10/10/2014 I have been diagnosed with Invasive Ductal Carcinoma, High Grade (Nottingham Score 9/9) What stage of breast cancer is that?
 Asked: 10/11/2014 My pathology report after breast biopsy read: sections reveal an aggregate of acini.
 Asked: 10/8/2014 I had a lumpectomy. Please clarify what this means - is it good news or bad news? Do findings increase my risk of recurrence? 1.
 Asked: 10/5/2014 Had lymph nodes removed with first breast ca dx in 1997 (DCIS, tubular carcinoma treated w/ lumpectomy and radiation).
 Asked: 10/5/2014 After several years of repeat mammograms& callbacks for additional views followed by ultrasound on 2 of those occasion- for density changes and asymmetry (that didn''t...
 Asked: 10/5/2014 My pathology on removed breast states resiudal 2.5 x 1.3cm.
 Asked: 10/1/2014 I had a lumpectomy/sentinel node biopsy after 34 days of Letrozele Invasive breast cancer diagnosis tumor 1.5x1.2 with overall tumor cellularity/ clean margins 2 lymph node #1, level...
 Asked: 10/1/2014 My pathology report is as follows: Rt.
 Asked: 9/29/2014 I just submitted a question and misspelled so many words.
 Asked: 9/29/2014 June 30th two punch biopsies read: A.
 Asked: 9/26/2014 newly dx with invasive ductal carcinoma - initial biopsy results: nottingham grage 6/9, tubules 3/3, nuclear grade 2/3, mitoses 1/3, tumor size 1.3 cm, ER...
 Asked: 9/26/2014 My pathology report states right sentinel #1 isolated rumor cells (ITCs) identified within one of 3 lymph nodes.(Immunohistochemical stain for pancytokeratin is positive within...
 Asked: 9/26/2014 could you pls tell me what ductal carcinoma in situ with comedonecrosis and epithelial calcifications, tumor size 0.1 cm greatest tumor dimension means? this result...
 Asked: 9/25/2014 How abnormal is it to have numerous cycts in both breast and also in the armpits ? Left:10 Right: 7 Please advise, thank you..
 Asked: 9/24/2014 i would like to know the grading of non-Hodgkin Lymphomas and the basis of the grading please, Thanks .
 Asked: 9/23/2014 My pathology report (ultrasound guided core biopsy) says: "Sclerosing lesion with usual ductal hyperplasia, columnar cell change and calcifications. Immmunohistochemical stains for CAM 5.2, p63 and smooth...
 Asked: 9/23/2014 My Mom''s pathology report is as stated: Invasive Ductal Carcinoma.
 Asked: 9/22/2014 My question: What does the below pathology report mean [in laymans terms? ] Also, is an excisional biopsy the same thing as a...
 Asked: 9/21/2014 I had a sterotactic core biopsy and the diagnosis was Fibrofatty breast tissue with focal minimal incidental atypical lobular hyperplasia.
 Asked: 9/15/2014 I had a sterotactic biopsy. No malignancy found, but because there''s "rare foci of flat epithelial atypia", doctor is recommending more invasive surgical biopsy.
 Asked: 9/15/2014 I was dignosed with invasive ductal carcinoma from a needle biopsy the after mastectomy with no treatment pathology report said no residual tumor and the...
 Asked: 9/15/2014 The National Comprehensive Cancer Network Guidelines dictates that a woman with a breast cancer tumor more than 1 cm regardless of onco score should have...
 Asked: 9/15/2014 I just had lumpectomy which revealed dcis high grade focally extending to within 1 mm of closest surgical margin.
 Asked: 9/14/2014 My pathology report states DCIS pTis 12 mm DCIS noted in three separate tissue blocks, solid grade 3 focal non expansive central necrosis.
 Asked: 9/14/2014 Hello,, what does it mean in simple terms when pathology reports reads, infiltrating ductal carcinoma of no special type??
 Asked: 9/12/2014 Hi there: I have been diagnosed with 2 biopsies to have an adenosis tumor and a hamartoma in the 2nd biopsy.
 Asked: 9/10/2014 What is a more favorable prognosis with all factors of a stage 1 breast cancer being the same......a 2 cm tumor with an onco score...
 Asked: 9/10/2014 Hi I am looking for an answer on the calculation of overall survival period in clinical trials. I came across a clinical trial explaining the effectiveness of...
 Asked: 9/9/2014 is vascular invasion and intravascular carcinoma the same thing? Path report says " We favor that the tumor at the margin is intravascular".
 Asked: 9/7/2014 Can you please clarify what this means "Nuclear Pleomorphism-Score 3: Vesicular nuclei, often with prominent nucleoli, exhibiting marked variation in size & shape, occasionally with...
 Asked: 9/6/2014 If currently undergoing radiation therapy for breast cancer, would there be any benefit in asking for the oncotype dx 21 to be completed on the...
 Asked: 9/6/2014 48 years, Biopsy results: right breast 9 o''clock - at least DUCTAL CARCINOMA IN SITU WITH COMEDONECROSIS, HIGH GRADE.
 Asked: 9/6/2014 my pathology reports this: lobular atrophy,fibrocystic change and focal columar cell change.
 Asked: 9/6/2014 Hx of Hodgkins disease with radiation to upper mantel..
 Asked: 9/6/2014 60 yr. old had skin sparing mastectomy for extensive DCIS with planned implant reconstruction.
 Asked: 9/4/2014 Could you please tell me what "deep margin positive for Intravascular Carcinoma" means? Thank you so much for your help!!! .
 Asked: 9/2/2014 I am currently 53 years old and menopausal since 49, Mamography found my Lump april7 and post needle biopsy confirmation of cancer I...
 Asked: 9/1/2014 I am a 59 year old and have a palpable breast cyst that has debris in it.
 Asked: 8/30/2014 invasive ductal carcinoma, Nottingham grade II, histological score 3, nuclear score 2, mitotic score 2 , overall size 1.3 (Vascular invasion negative, surgical margin positive
 Asked: 8/28/2014 The lumpectomy report showed invasive papillary carcinoma grade 2 tumor was 2 x 1.5 x1.5 cm doctor suggested mastectomy as report showed foci of intraductal...
 Asked: 8/28/2014 Lillie, this is a lab test question, not pathology because I didn''t know exactly where to put it.
 Asked: 8/27/2014 im 41,family history of BC several relatives...I have 19x10x14mm lump...6 o clock ....I had mammogram then u/s then fna then core biopsy Fna results...
 Asked: 8/25/2014 After a core needle biopsy on a close to the chest wall intraductal papilloma resulted in non-atypia benign cells, an excision was recommended.
 Asked: 8/22/2014 Are HERS 2 receptors only found in the body other than the breast? If so,where and is this the reason the treatment is so aggressive ?
 Asked: 8/22/2014 My surgical pathological report from my left breast excision for papillomatosis reads: few foci of lobular carcinoma in situ.
 Asked: 8/22/2014 What does pathologic staging: pT2, pNx, preliminary stage II.
 Asked: 8/22/2014 I have Lupus. I read that radiation is not a good choice after a Lumpectomy because your skin would be too sensitive to the side effects.
 Asked: 8/21/2014 Please help me understand the following : Left breast calcifications, stereotactic biopsy.
 Asked: 8/23/2014 What is atypical apocrine hyperplasia "clinging type"? Thank you for getting back to me..
 Asked: 8/20/2014 When is need for chemo determined? Is oncotypeDX test always performed? I have invasive ducal grade 3, her2-, est rec+, prog rec-, ki 67= 60%...
 Asked: 8/20/2014 My pathology report states: histological grade 3, nuclear grade 1, Mitotic features average < 5MF/10HPF.
 Asked: 8/18/2014 i have a mixed breast toumor aka imc, are treatments same as for idc????
 Asked: 8/18/2014 The lumpectomy report showed invasive papillary carcinoma grade 2 tumor was 2 x 1.5 x1.5 cm doctor suggested mastectomy as report showed foci of intraductal...
 Asked: 8/16/2014 My pathology report done after lumpectomy, does not contain information about receptors of the tumor, HER 2 etc.
 Asked: 8/16/2014 is there a reference chart or I can.
 Asked: 8/16/2014 I was diagnosed with invasive ductal carcinoma, nottingham grade 2.
 Asked: 8/16/2014 I have just received my oncotype dx results which came in at 15.
 Asked: 8/14/2014 i am a 58 year old with a strong family history of breast cancer.
 Asked: 8/14/2014 Pathology Report...what does the following mean?? 1) Rare foci of lobular carcinoma in situ (x2) upper outer quadrant 2) Proliferative fibrocystic change with florid duct hyperplasia, foci...
 Asked: 8/14/2014 Test Result from needle core biopsy: Right Breast Intraductal Papilloma present in four of approximately five core fragments, longest 0.4 cm.
 Asked: 8/14/2014 Hi, I was just diagnosed with Invasive ductal carcinoma.
 Asked: 8/14/2014 How is Her2 -ve different from just Her2-? ER and PR both negative..

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