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Understanding Pathology Results
Questions explaining and understanding pathology results.
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 Asked: 1/18/2018 What does it mean ER diffusely positive, CK 5/6 focally absent and p63 retained around ducts? Thanks..
 Asked: 1/16/2018 What does a Ki-67 score of 5.8 mean?
 Asked: 1/16/2018 How do cancer cells get to the axillary lymph nodes? What method of transport do they use to get there? Blood? Lymph...
 Asked: 1/12/2018 I have been diagnosed with a reocurring of dcis-stage o agai and non invasive-in the same area as 2016.
 Asked: 1/10/2018 what is well differentiated invasive ductal carcinoma with calcifications (tubule formation 2/3, nuclear pleomorphism 2/3, mitotic counts 1/3), measuring 1.3 cm in maximal
 Asked: 1/7/2018 Diagnosed with 2cm Grade 2/3 DCIS, .35cm IDC, grade 2, ER+, PR+, HER2-, had 2 sentinel nodes removed and found isolated tumor was in one...
 Asked: 1/7/2018 How can clean margins be obtained if the SLN nodes (2/3) are positive with lymphovascular invasion?
 Asked: 1/6/2018 I had a lumpectomy and SNB, 1/3 positive nodes.
 Asked: 1/4/2018 My stereotactic breast biopsy is undergoing receptor test now, and I am waiting for the testing result.
 Asked: 1/3/2018 If you could please explain what the following means it would be appreciated: DIAGNOSIS: Breast, right, core needle biopsy: -Benign fibroglandular mammary tissue (please see microscopic description) -Microcalcifications identified MICROSCOPIC...
 Asked: 1/1/2018 You and this site have been a godsend to me.
 Asked: 12/30/2017 I have had three opinions and still no clear answer.
 Asked: 12/30/2017 R breast nodule metaplastic carcinoma 7 MM.
 Asked: 12/27/2017 Had surgery by VA with partial penectomy.
 Asked: 12/21/2017 I’m surprised they use the terminology “approaches the threshold for DCIS”, isn’t it one or the other ADH or DCIS? I''m assuming there are concerns...
 Asked: 12/16/2017 Oct-2012: DCIS right breast, grade 3, ER+ PR- TX: Lumpectomy, 35 radiations, 5 years Exemestane Oct-2017: DCIS right breast, same location, grade 3, comedy type, size upto...
 Asked: 12/15/2017 The pathology report does not clearly state (so I can understand) whether the FISH test finds her2 + or Her2 -.
 Asked: 12/15/2017 ‘Is a Ki-67 an expected result with a core and/or surgical biopsy? I don’t have one on either of my reports..
 Asked: 12/15/2017 I was diagnosed with "ductal carcinoma, 1.3 cm with tubular and invasive cribriform patterns, modified bloom richardson grade 1 of 3.
 Asked: 12/13/2017 What does Nottingham score 8, stage PT1c, glandular differentiation 3, Nuclei 3, Mitosis 2, size 1.3cm, estrogen receptor: positive(99% strong) , Progesterone receptor Positive (95%...
 Asked: 12/13/2017 Hello. I was just diagnosed with Invasive Ductal Carcinoma with Micropapillary Features.
 Asked: 12/11/2017 Hello, I am a young 31 women who diagnosed last year with breast cancer.
 Asked: 12/9/2017 Sternal mets on CT & bone scan and pre-sternal nodule which was biopsied.
 Asked: 12/4/2017 What does the following from my pathology report mean: Distance of DCIS from closest Margin: Per the consultation report from Mayo Clinic,...
 Asked: 12/4/2017 Age 48. Mother had mastectomy at 42 and 48, passed at 63, I had a Mam 11/6, Compression Mam 11/7, Radiologist pointed out a single cluster of microcalcifications that was an area of concern due to the fact that it was a "single" cluster and the way they were clustered.
 Asked: 11/30/2017 Focal asymmetry on mammogram. U.S.
 Asked: 11/30/2017 Hello. Can you explain how important LVI is to prognosis? I had a small (9mm) tumor, strongly ER and PR+, HER2-, but lymphovascular invasion was identified.
 Asked: 11/30/2017 Dear Lillie, 1. My HMO surgical sample was not retested to confirm my ER, PR, HER2 and Ki-67 by my HMO or with the Oncotype DX/Genomic Health, score of 20.
 Asked: 11/29/2017 does oncotype dx consider focal lymphvascular invasion when they calculate the score ? .
 Asked: 11/29/2017 would you mind explaining focal lvi to me.
 Asked: 11/28/2017 How does the PR affect outcome? I am ER+, PR- and HER2-.
 Asked: 11/28/2017 DMG - THORACIC ........................... Nature of Material Right lung mass biopsy FINAL HISTOPATHOLOGY REPORT 28-11-2017 Gross Description Received multiple cores aggregating to 1x0.8cm submitted entirely. Microscopic Description Right lung mass biopsy: Adenocarcinoma. Intracellular mucin is...
 Asked: 11/27/2017 I just had bilateral mastectomy and all the doctors were happy with the pathology report which showed a 2 cm IDC, 0/2 nodes negative,...
 Asked: 11/26/2017 I had grade 2/3 mixed ductal/lobular, 1.5cm with focal LVI (lymph)and ki67% of 19.
 Asked: 11/25/2017 My pathology report says I have triple negative invasive ductal carcinoma grade 2 with prominent apocrine features and minor component of ductal carcinoma in situ,...
 Asked: 11/22/2017 Hello , my aunt was diagnosed with breast cancer in 2012.
 Asked: 11/21/2017 The 1st surgery report said 3 margins were DCIS positive, the 2nd surgery removed 3 pieces tissue for new margins.
 Asked: 11/13/2017 The first surgery was done in this June, pathology lab result were: INVASIVE CRIBRIFORM ADENOCARCINOMA associated with IPA + DCIS.
 Asked: 11/10/2017 My Mom had a lumpectomy on 10/17/2017.
 Asked: 11/8/2017 Hi Lillie. I have a question about the question that was just asked about being highly estrogen positive.
 Asked: 11/7/2017 Some studies have shown that women with high estrogen levels in their breast cancer have twice the chance for a recurrence than women with lower...
 Asked: 11/3/2017 Biopsy pathology report for testing of PR states "technically inadequate".
 Asked: 11/1/2017 Good morning. My pathology report says "paraductal inflammation with microcysts" this to me sounds like mastitis.
 Asked: 10/31/2017 I am a 63 year old female 2 weeks post bilateral mastectomy with sentinel node biopsy due to malignant neoplasm of right breast - ILC.
 Asked: 10/29/2017 Hello. Im 46 years old and just underwent a needle core biopsy in my left breast.
 Asked: 10/29/2017 Why is the margin size after lumpectomy for DCIS suggested to be 2mm and only 1 mm for invasive? I had lumpectomy in 2015...
 Asked: 10/29/2017 Core biopsy result ... fibrocystic change with duct epithelial hyperplasia.
 Asked: 10/26/2017 How often are Pathology reports wrong? I had a stereotactic biopsy done and the radiologist was expecting to see either a radial scar or...
 Asked: 10/25/2017 Now that margin size matter, is 0.5cm considered good clear margin after lumpectomy?Is there a minimum clear margin size that doctors aime for now? .
 Asked: 10/23/2017 How important is it to know my ki67 number? It was not indicated on my pathology report.
 Asked: 10/22/2017 My pathology report shows ER-,PR-, fish-pending. Tumor is 2.6 cm on right breast with a Nottingham score of 9 of 9, grade 3 tumor with zonal necrosis associated with invasive carcinoma.
 Asked: 10/21/2017 How much would it cost to get a second opinion from Johns Hopkins (pathology from surgical specimen) regarding my ER, PR, HER2 status and Ki-67?..
 Asked: 10/20/2017 I Just got back the biopsy report from the pathology dept and was wondering if you can please explain it to me.
 Asked: 10/20/2017 1. Are there clinical studies to see whether all triple negative breast cancer patients need chemo? 2.
 Asked: 10/20/2017 What does ER-, PR+, HER2- mean?
 Asked: 10/20/2017 Hello- I just had a bilateral masectomy for DCIS in one breast.
 Asked: 10/20/2017 Breast biopsy, needle core, left mass, 6:00 At least grade 2 invasive ducal carcinoma, greatest dimensions 3x 1 mm in this specimen ER negative PR negative HER2/neu POSITIVE Focal intermediate...
 Asked: 10/20/2017 I was recently diagnosed with "DCIS, grade 2, with expansile comedonecrosis." That is all the pathology says.
 Asked: 10/20/2017 In February I had a lumpectomy of left breast that came back as a fibroadenoma.
 Asked: 10/16/2017 does Johns Hopkins inform patients that they are in a phase 3 trial with the Genomic Health Product called Oncotype DX for breast cancer over the...
 Asked: 10/15/2017 Is it true that AJCC, American Joint Committee on Cancer, 8th edition, has approved the Genomic Health company, which is still in phase...
 Asked: 10/14/2017 I have been told my tumor had micropapillary features.
 Asked: 10/13/2017 I have been told my tumor had micropapillary features.
 Asked: 10/13/2017 Hi, I recently had this diagnosis as a result of lumpectomy: ADH with microcalifications, apocrine metaplasia, ductal hyperplasia, papillary ductal hyperplasia, microcysta, adenofibrosis and stromal...
 Asked: 10/13/2017 Hi Lillie, Thank you for your response to my prior inquiry.
 Asked: 10/11/2017 Hi Lillie, Thank you for your reply to my 10/9/17 question.
 Asked: 10/11/2017 I had lumpectomy with idc/positive present as two foci each less than 1 mm at the inked margin.
 Asked: 10/9/2017 Knowing that mistakes can be made in a lab, why wouldn''t the test for breast cancer (ER+, PR+, HER2-) be repeated on a surgical sample?..
 Asked: 10/9/2017 My MRI said there is a circumscribed mass 1.9 x1.4 x 2.2 cm with a volume of 2.92 cc.
 Asked: 10/9/2017 I just am diagnosed with dcis stage 0, I just had mastectomy on right breast, no cancer found in lymph node but after pathology of...
 Asked: 10/8/2017 Is it standard of care to do ER,pr,her2 measurments on surgical sample if it was done on a prior core biopsy?
 Asked: 10/6/2017 Can you please explain what all this means please Ductal ccarcinoma-in-situ: Size: 24mm Nuclear grade: High Architecture: Solid and cribriform Necrosis: Present (comedo) Microcalcification: Present Additional comments: Atypical lobular hyperplasia / Lobular...
 Asked: 10/5/2017 I had a core needle biopsy performed on a 6mm by 7mm lobular hypoechic mass at the 3:00 position. The results cam back today as "negative"...
 Asked: 10/4/2017 It is my understanding that for invasive carcinoma the margins need to be free of cancer, >0.2cms, and in the presence of DCIS they need...
 Asked: 10/4/2017 Hi, I was diognosed with Ductal carcinoma-in-situ: Size: 24mm Nuclear grade: High Architecture: Solid and cribriform Necrosis: Present (comedo) Microcalcification: Present what does this mean please?
 Asked: 10/4/2017 Thank you for taking my question. My mother is 78 years of age and was given these results by a PA.
 Asked: 10/4/2017 What is more predictive of survival.......tumor size or onco score? Thank you..
 Asked: 10/4/2017 I still don''t understand the difference between HER2+ and HER- status.
 Asked: 10/3/2017 Gets more confusing. Got more info on my pathology and its says ER positive (71% strong intensity nuclear staining) PR Negative and HER-2 score 2+ (equivocal) FISH analysis will be performed.
 Asked: 10/2/2017 Should I be concerned that PASH was part of my pathology report? Thank you very much! PATHOLOGY REPORT: Right breast, upper outer, with calcifications, stereotactic core needle...
 Asked: 10/2/2017 IDC .6cm Nottingham total 4 of 9 Lymphovascular :absent Lobular carcinoma in sit-up nuclear grade 1-2 Ductal carcinoma in situ present Architectural pattern od DCIS: solid and cribriform Nuclear grade...
 Asked: 9/28/2017 My 70yr old Mom received a diagnosis that favors breast papillary carcinoma(solid variant).
 Asked: 9/28/2017 Hi there, I was hoping you could help me understand my pathology report a little better.
 Asked: 9/28/2017 My blood work indicates that I have a low anion gap (from 18 six months ago to 8).
 Asked: 9/27/2017 "Rare foci of atypical lobular hyperplasia" on the vacuum assist core needle biopsy pathology report.
 Asked: 9/27/2017 The pathology report for my level 1 and 2 axillary lymph node dissection says specimens show "granulation tissue with chronic inflammation, fat necrosis, foreign body...
 Asked: 9/27/2017 Could you explain to me what focal lymphovascular invasion is? My oncotype was a 14.
 Asked: 9/26/2017 Here is from pathology lab report: Histologic Type Invasive cribriform carcinoma Invasive mammary carcinoma associated with encysted papillary carcinoma Histologic Grade (Nottingham Histologic Score) Glandular (Acinar)/Tubular Differentiation Score 2 (10% to...
 Asked: 9/26/2017 Hi Lillie - I tried to post a message last week, but I never got the e-mail saying the original question went through (I must''ve...
 Asked: 9/23/2017 Hello. I had an ultrasound guided biopsy followed by a MRI vacuum biopsy.
 Asked: 9/22/2017 what does pT1b pNX mean. I had a full hysterectomy done 7/31/2017.
 Asked: 9/22/2017 hello.. im 28yrs old.
 Asked: 9/19/2017 I was diagnosed w/dcis grad 3 multi focal & had a total mastectomy I just noticed that surgical path report states dcis w/lobular extension.
 Asked: 9/19/2017 IDC, 1.6cm tumor, stage 1a, grade 2, clear nodes 100% ER positive, PR negative, HER2 negative.
 Asked: 9/19/2017 I am almost 70 yr, diagnoses is tissue sample A right breast lumpectomy, DCIS , cribform type grade 2 of 3 identified, margins negative, selerosing...
 Asked: 9/18/2017 I was diagnosed with atypical hyperplasia 0n left breast and right breast with lobular carcinoma in situ with a complex schlerosing lesion with...
 Asked: 9/17/2017 hello and thank you in advance. Do you know if being post menopausal and being on arimidex for 2 years could affect alkaline phosphate levels.
 Asked: 9/17/2017 I am almost 70 yr, diagnoses is tissue sample A right breast lumpectomy, DCIS , cribform type grade 2 of 3 identified, margins negative, selerosing...
 Asked: 9/15/2017 what does it mean when path report says duct.

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