Ask an Expert: Understanding Pathology Results

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Understanding Pathology Results
Questions explaining and understanding pathology results.
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 Asked: 4/28/2017 Hi, My MRI states there is a non mass enhancement in a linear distribution with clumped internal enhancement measuring 6 TV X 15 AP X 7mm.
 Asked: 4/26/2017 I have recently been diagnosed with invasive ductal carcinoma.
 Asked: 4/26/2017 Here is part of lab report from biopsy: Core biopsy of breast tissue is examined with three separate levels. There are few dilated ducts filled with atypical...
 Asked: 4/19/2017 hi there my sister is days away from getting a mastectomy.
 Asked: 4/19/2017 Hi Lillie - Thanks for this wealth of information that you take the time to put out here on the web.
 Asked: 4/19/2017 I have been diagnosed with a fibro-adenoma of my right breast and thE Drs.
 Asked: 4/18/2017 I had a recent breast biopsy an results said: stromal fibrosis, mild adnenosis, modest chronic inflammation, an rare microcalcifications.
 Asked: 4/11/2017 Everything I have read on the subject indicates that luminal "a" breast cancer is most likely to metastisize to the bone if it goes to stage 4.
 Asked: 4/11/2017 The pathology report from my breast biopsy (resulting from changes from last year''s mammogram, now showing clusters of microcalcifications seen on my current mammogram) indicates...
 Asked: 4/6/2017 Can you provide any more details as to why this CA-125 number could be rising and why my oncologist is recommending a PET scan?..
 Asked: 4/5/2017 I have had a rising CA 125 number in my test results for the past 3 months.
 Asked: 4/5/2017 Tissue code T1.
 Asked: 4/5/2017 Can you explain what these lumpectomy findings mean: tissue reveals extensive sclerosing adenosis, papillomatasis, columnar cell changes, aprocrine metaplasia, fibrosis, and duct all calcifications
 Asked: 4/3/2017 My pathology report stated the following and I just wanted an explanation: DCIS extending into lobules high nuclear grade with comedonecrosis and calcifications.
 Asked: 4/2/2017 a 4mm spot was found in my right breast by tomosynthesis.
 Asked: 4/2/2017 I recently had a FNA for a thick walled complex cyst.
 Asked: 4/2/2017 What is a "heterogeneous myocardial infarction of cells"?
 Asked: 3/29/2017 lumpectomy 3/13/17..Invasive Carcinoma..50 mm..Tubule diff=3,nuclear pleomorphism=2, mitotic rate=1 (Nottingham total=6), single focus i.c.
 Asked: 3/29/2017 I had right lumpectomy and my pathology report states Invasive ductal carcinoma, grade 3 of 3 (which I knew) but it also states: Ductal carcinoma...
 Asked: 3/26/2017 I had bilateral mastectomy because of IDC with pT3 score.
 Asked: 3/22/2017 I know that I am ER+ (90%) and PR+ 95%.
 Asked: 3/21/2017 lumpectomy 3/13/17..Invasive Carcinoma..50 mm..Tubule diff=3,nuclear pleomorphism=2, mitotic rate=1 (Nottingham total=6), single focus i.c.
 Asked: 3/21/2017 Hi, which is more accurate when measuring a tumor, pathology or mri?
 Asked: 3/21/2017 Dear lilie sorry for my spelling mistake in my previous question regarding pathologists confusion it was ductal vs tubular not lobular..
 Asked: 3/21/2017 After surviving Breast cancer with chemo and double mastectomy and now my friend has cancer for the second time.
 Asked: 3/20/2017 I just want to ask you regarding my pathology report after chemo..
 Asked: 3/20/2017 First off I would like to thank you for putting my mind at ease many times.
 Asked: 3/20/2017 Ki67 50% TNBC STAGE 1 how serious is this diagnosis?
 Asked: 3/19/2017 I am 43 years old. No history of breast cancer in family, younger sister had osteosarcoma last year at 41.
 Asked: 3/19/2017 Grade 3 ICD estrogen +pr+her2- 10 mm and 1/4 node positive 5 mm.
 Asked: 3/17/2017 My IDC was classified as ER+ (>90%), PR+ (>90%), HER2+++(IHC), KI-67(47%), p53(86%) stage 2, nottingham grade 3.
 Asked: 3/16/2017 I was diagnosed with stage 2 grade 2 idc er+.
 Asked: 3/16/2017 Original Pathology report after 2 stereotactic vacuum assisted biopsies found Atypical Lobular Hyperplasia, Itraductal Pappiloma with sclerosis, clusters of microcalcifications
 Asked: 3/14/2017 what does pT1cNO disease mean in breast cancer.
 Asked: 3/13/2017 What does it mean to have "cribriform growth pattern with microlumens and transluminal epithelial bridges"? What does it mean when "p63 stain highlights myoepithelial...
 Asked: 3/12/2017 My ductal carcinoma surgery was January 16 - mastectomy 1.8cm tumour ER+PR+ Her- no lymph node involvement (0 of3) grade 2 - Oncotypedx score of 21.
 Asked: 3/10/2017 Does Oncotype Dx confirm or deny her2 in someone with mixed results.
 Asked: 3/10/2017 Hello. I am trying to understand why the pathology re: LVI would differ between pathology from core needle biopsy and lumpectomy.
 Asked: 3/10/2017 Biopsy was benign but showed radial scar with impression being suspicious.
 Asked: 3/9/2017 I recently had a double mastectomy for DCIS (grade 2)/LCIS in my left breast and grade 1 stage 2 Invasive Ductal Carcinoma in my right breast.
 Asked: 3/9/2017 My oncologist conferred with a handful of other oncologists to determine if treatment was necessary.
 Asked: 3/8/2017 My oncologist has suggested that since my IHC was 3+ for her2 but my fish was not amplified I should still get Herceptin because if...
 Asked: 3/8/2017 Which is the most definitive for Her2? IHC or fish? My IHC was 3+ but Fish said not amplified.
 Asked: 3/7/2017 Lillie, my post lx report came back that i was ER and PR+.
 Asked: 3/3/2017 I am so grateful to you for helping so many of us...thank you.
 Asked: 3/3/2017 Would the pathology report from the needle core biopsy and the lumpectomy be the same for estrogen, progesterone and the her-2 gene? And if...
 Asked: 3/2/2017 Hello What treatment would be considered for hormone profile showing weak er and pr positive (both 5%, light) and her2 negative.
 Asked: 3/1/2017 Confused with my her-2 Test, the first part reads her-2/neu protein (4B5 antibody): equivocal 2+/3 30%) Fish test reads gene status not amplified, her-2/cep17 ratio...
 Asked: 2/25/2017 I had my lumpectomy of my left breast this week.
 Asked: 2/24/2017 I have a new abnormality on my MRI after having some biopsies almost three months ago.
 Asked: 2/24/2017 Hi, I''ve had three biopsies - and they found ALH, radial scar, adenosis etc (all in the right breast).
 Asked: 2/24/2017 what does hyalinized fibroadenomatoid change mean after a core needle biopsy?
 Asked: 2/21/2017 Another question regarding onco score. If I have a 1.3 cm tumor with no lymph node involvment and onco score of 8 my recurrence risk is 6% over 10 years according to my report.
 Asked: 2/21/2017 Had stereotactic core needle biopsy march 2014.
 Asked: 2/18/2017 I was diagnosed with fibrocystic change with nodular pseudoangiomatous stromal hyperplasia, cysts, apocrine metaplasia, adenosis, stromal fibrosis and microcalcifications in benign ducts and stroma
 Asked: 2/18/2017 I had a question about onoctype. Say someone has a 1cm tumor with negative nodes versus a 4.5cm tumor with negative nodes and they both had the same onoctype score.
 Asked: 2/18/2017 Thank you so much for yr answer to my question i just posted (tnbc 1,2 cm).
 Asked: 2/17/2017 Hi. Was diagnosed april 2016 tnbc 1,2cm 0/16 nodes ki67 50% grade 3.
 Asked: 2/15/2017 I''m 52 Diagnosed Nov 1st 2016 Left breast multi-focal IDC 3.5cm grade 2 ER85% PR8% KI67 18% 3/5 nodes positive on path Stage 2B Dec...
 Asked: 2/13/2017 Hi Lillie! There are so many scary things out there about Luminal B breast cancer.
 Asked: 2/11/2017 ER positive 90% strong intensity nuclear staining, PR positive 90% strong intensity nuclear staining, HER 2 negative (0 and focal 1+ staining , Ki-67 12%...
 Asked: 2/8/2017 What does Moderately-differentiated invasive ductal carcinoma with minimal stromal fibrosis mean?
 Asked: 2/8/2017 Hi Lillie and many thanks for all your help.
 Asked: 2/6/2017 I was diagnosed with ER+, PR-, Her2-,tiny 5mm tumor.
 Asked: 2/6/2017 My pathologic staging of colorectal cancer says pT2NoMx, please advise which stage is this and what are the survival..
 Asked: 2/5/2017 Trying to understand what biopsy report means.
 Asked: 2/5/2017 My wife was diagnosed with breast cancer in 2013.
 Asked: 2/4/2017 My biopsy report says P40 immunostains are positive.
 Asked: 2/4/2017 Is a diagnosis DCIS, Nuclear Grade 3of 3, with solid and comedo architectural patterns.
 Asked: 2/3/2017 My pathology report says I have DCIS, Nuclear Grade 3of 3, with solid, cribriform, and comedo architectural patterns.
 Asked: 2/2/2017 Any follow up needed for core breast biopsy for results of (1)enlarged lobular units with columnar alteration and mild usual type epithelial hyperplasia (2) calcifications...
 Asked: 2/1/2017 I had a stereotactic biopsy and it came back with fibrocystic change with nodular pseudoangiomatous stromal hyperplasia, among other things.
 Asked: 2/1/2017 my mammogram read small mass in the upper posterior right breast is stable and appears to be a lymph node.
 Asked: 1/30/2017 Is there a difference in a sentinel node being positive and a lymph node being positive for cancer??
 Asked: 1/30/2017 I am confused with the results and wondering if someone could help me understand the pathology report.
 Asked: 1/29/2017 Does Nottingham score of 6( with mitotic grade of 1, er+, pr-, her2 neg, ki67 of 60, 2.2 cm, no node involvement, lvi identified.
 Asked: 1/28/2017 At time of biopsy my ki67 was 35 on 12/7.
 Asked: 1/28/2017 Does a ki67, of 60, mitoic grade 1, 2.2cm, with lvi mean chemo is necessary.
 Asked: 1/27/2017 Does a ki67 percentage of 60 outweigh a multicultural grade of one and thus throw the oncotypedx result into the high risk category?
 Asked: 1/27/2017 I have been diagnosed with stage 2a idc.
 Asked: 1/27/2017 I had by stereotactic biopsy completed, but am still concerned.
 Asked: 1/26/2017 Can someone explain this please? I can find the definition of "usual" & "atypical" but this seems to be a combo? Any help is greatly...
 Asked: 1/26/2017 My mother was diagnosed with a breast cancer and subjected to the surgery.before the surgery the ultra sound scan indicated two enlarged lymph nodes.but in...
 Asked: 1/19/2017 biopsy report: detached fragments of markedly atypical cells, highly suspicious for carcinoma.
 Asked: 1/18/2017 5/17/16 had partial mx for widespread dcis left breast (no mass nothing palpable saw on mammo and MRI).
 Asked: 1/11/2017 I have IDC stage 1A breast cancer. Had lumpectomy on Dec 2016, the pathology report said: FOCI SUSPICIOUS FOR LYMPHOVASCULAR INVASION. After lumpectomy I had sentinel surgery, found...
 Asked: 1/10/2017 My biopsy reports contains the following: Apocrine metaplasia with mild atypic (See Note). Micropapilloma Micro calcifications are identified in the apocrine areas as well as the micropapilloma. NOTE: extensive...
 Asked: 1/7/2017 In the following path report below, am I correct in understanding the nottingham score to be as follows: Mitotic rate: 1-10 per 10 /hpf...
 Asked: 1/3/2017 Hi, 8 gauge vac stereotactic biopsy found DCIS high grade with comedo necrosis, microcalcs, ER+/PR+, no invasive cells in the sample.
 Asked: 1/3/2017 Just recently received my pathology report from lumpectomy due to high grade DCIS ER/PR neg 7cm.
 Asked: 1/2/2017 Please tell me what this means as it relates to treatment options: A. Right breast, 11o''clock N+3, needle core biopsy (slides A 1x3 and six fmmunohistochemical stain...
 Asked: 1/1/2017 Hi, I was diagnosed with ALH, and of course it said that the E-cahedrin (I think I spelled it right) was negative or gone (I''m...
 Asked: 12/29/2016 Hello.. I am 28 years old and currently breastfeeding my 2nd child.
 Asked: 12/29/2016 To whom it may concern, I did the laboratory test for ANA.
 Asked: 12/28/2016 Sterotactic biopsy R breast 6:00 report states:Sections show high grade DCIS with apocrine features and central necrosis.
 Asked: 12/26/2016 After surgery, a 43 years female patient has the followings in her histopathology and immunocyto-histochemistry reports for breast cancer: Grade 2 : Scored as 6 (Nottingham...
 Asked: 12/21/2016 What does lymphovascular space invasion:focally present in breast cancer.
 Asked: 12/20/2016 Diagnosed w/ bilateral synchronous BC 2 years ago.
 Asked: 12/14/2016 WHat does it mean when an oncologist referrs to a cancer as Luminal B? I know its a general term but I am not sure what it is indicative of..
 Asked: 12/14/2016 I apologize I asked a question and left out this info: I am ER+ PR+ Her2- OncoDX 20.

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