Ask an Expert: Understanding Pathology Results
 
 
 
 

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Understanding Pathology Results
Questions explaining and understanding pathology results.
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 Asked: 4/16/2018 My wife 45 years old just completed her lumpectomy iand was staged as T1N1MO ,1 A , clean margins with an indolent tumour...
 Asked: 4/16/2018 How long should I expect to wait to hear about Ki-67 results?
 Asked: 4/16/2018 My understanding is that ASCO and NCCN have different recommendations on the relevance of Oncotype DX screening results in lymph node positive cases (assuming also...
 Asked: 4/16/2018 Hello. I was diagnosed Feb 2018 with TNBC, 1 cm, stage 1, no nodes involved.
 Asked: 4/12/2018 All the charts indicate that for luminal A breast cancer (slow growing and low grade) the odds for a recurrence are more likely after 5 years.
 Asked: 4/12/2018 Please help me out My ultrasound findings say:In the retreoareolar region of the right breast along the 12 o''clock radial there is 11mm complexs space occupying...
 Asked: 4/9/2018 Options for estrogen positive, progesterone negative and her2 negative .
 Asked: 4/3/2018 my oncotype dx waa low risk at 14.
 Asked: 3/26/2018 Hi ~ I''ve been trying to find out the meaning of parts of my pathology report online to no avail.
 Asked: 3/22/2018 I had surgery to remove an enlarged palpable axillary lymph node.
 Asked: 3/22/2018 I had BMX after dose dense AC-T chemo, 2.1 cm of residual DCIS with 3 foci of micro invasions was found in the breast.
 Asked: 3/20/2018 Hi there. My lumpectomy showed multiple radial scars,columnar cell change/hyperplasia, apocrine cyts, no unequivocal atypical.
 Asked: 3/14/2018 Help with understanding diagnosis: Following an excisional biopsy left breast: Diagnosis: left Breast tissue: Biopsy site changes Fibrocystic changes, nonproliferative No evidence of atypia or malignancy
 Asked: 3/8/2018 Hi,I had a partial mastectomy and it was free of cancer but they found an area of 5cm ×3cm×3cm of a trabucalated scar and inflammation...
 Asked: 3/7/2018 Hello, My mo sent my pathology slides out per my request and now they are requesting the blocks.any reason why they would need them?
 Asked: 3/6/2018 What does this all mean in plain English? I have my oncology appt next week and want to go in educated.
 Asked: 3/5/2018 Hello, My breast biopsy report says Firbroednoma with myxoid changes.
 Asked: 3/5/2018 Hello and thanks for your service I am outside the USA this year & know that CTC and biomarkers aren’t standard practice.
 Asked: 3/2/2018 IDC from core bx. Low grade necrosis absent, lymphovasc invasion absent, calcification absent, ER receptor - positive 100%, PR receptor positive 100% HER2 equivocal submitted for FISH, Mib-1 proliferation index intermediate.
 Asked: 3/2/2018 I was tapering off bio-identical hormones for 2 months before my surgical sample.
 Asked: 3/2/2018 I viewed your answers to another posted question 3/1/2018 regarding testing the surgical sample by hospital/clinic MD versus Genomic Health, maker of Oncotype DX for...
 Asked: 3/2/2018 what does it mean when a path report reads "ADH displays solid and cribriform growth with apocrine features and calcifications" on biopsy of micro calcification...
 Asked: 3/2/2018 I have a solid 2.5 cm breast mass.
 Asked: 3/1/2018 My surgical tissue sample was not tested for ER, PR, HER2.
 Asked: 3/1/2018 Is the doctor responsible for diagnosing and forming a treatment plan for a patient or does the patient have to make the treatment plan for...
 Asked: 2/27/2018 I have received my pathology report after a core breast biopsy.
 Asked: 2/27/2018 63 y.o. with IDC grade 1, estrogen 90% positive progesterone 80 % positive, Her-2 neg (FISH), Ki-67 9%.
 Asked: 2/26/2018 I have just found out I am cancer-free after six rounds of chemotherapy! I was estrogen and progesterone negative but HR Positive.
 Asked: 2/23/2018 My pathology after core biopsy states fibrocystic changes with fibrosis including PASH, columnar cell hyperplasia, multifocal sclerosing adenosis, apocrine metaplasia
 Asked: 2/22/2018 I am a 54 yo WF, family history of breast cancer.
 Asked: 2/22/2018 I am 1 week post bilateral mastectomy for 2.8 cm DCIS.
 Asked: 2/20/2018 Follow up question. Thank you for clarifying things for me.
 Asked: 2/19/2018 The pathology of my second lumpectomy say: Left breast, anterior margin, excision: DCIS, low nuclear grade, cribriform and micro papillary pattern with focal necrosis, largest...
 Asked: 2/19/2018 First of all thankyou for taking the time to answer my questions.
 Asked: 2/19/2018 metaplastic carcinoma. What is survival rate.
 Asked: 2/19/2018 Hi. Newly diagnosed IDC Grade 3.
 Asked: 2/15/2018 Thank you for help. Hope in correct subject area or pls move! Just had CYP etc tests (life of bad responses antidepressants, pain, migraine etc meds).
 Asked: 2/14/2018 Thank you for answering the first part of my question regarding the CYP2D6 test.
 Asked: 2/13/2018 In August I will be 5 year survivor for stage 1 breast cancer.
 Asked: 2/11/2018 1. Left breast, excision with wire-guided localization: Invasive ductal carcinoma, Nottingham combined histologic grade 1 (tubules 2, nuclei 2, mitoses 1) Two foci of invasive carcinoma identified, largest focus measures 2.5cm in greatest dimension.
 Asked: 2/8/2018 I am having a breast biopsy for an indeterminate palpable breast mass confirmed by diagnostic mammogram and ultrasound.
 Asked: 2/2/2018 Two masses in the same breast: #1 Invasive moderately differentiated duct carcinoma 3 mm mass #2 Invasive poorly differentiated duct carcinoma with focal necrosis and calcifications 1.3...
 Asked: 2/1/2018 If your biopsy shows both Lobular and Ductal Atypical cells, and lumpectomy removes these cells-does your risk of developing breast cancer decrease? Or do...
 Asked: 1/31/2018 If additional tumors are found by surgical sample after a core biopsy should the specimen and each tumor be tested again for Estrogen, progesterone and...
 Asked: 1/29/2018 Hi Lillie. Is a her2- tumor less aggressive than a her2+ one? I know grade tells how aggressive a tumor is.
 Asked: 1/30/2018 I was diagnosed with ER/PR negative, HER2+ breast cancer, Stage 3 with 5 nodes postive and a 6mm tumor.
 Asked: 1/28/2018 What are the implications/significance if lymphovascular invasion is identified? Does it affect treatment recommendation? Risk of recurrence? .
 Asked: 1/26/2018 Can you explain Ki67, how it is used and if it is important since it’s Considered difficult to use without consistent methodology in pathology?
 Asked: 1/26/2018 Can you please explain an "Equivacol" HER2 result? IHC 2+ and FISH heterogeneity of HER2/neu gene amplification .
 Asked: 1/26/2018 I received standard treatment for TNBC. Neoadjuvant ac+t, surgery and radiation.
 Asked: 1/26/2018 "no lymphovascular invasion identified" yet 1/5 nodes (SLNB) positive, how did cancer cell(s) travel to node? What is the significance/importance of no lymphovascular involvement...
 Asked: 1/25/2018 My 1/23 question w/pathology results relates to concern re metastasis/survival as a recent ''Ask an Expert'' answer was 99% 5-yr.
 Asked: 1/24/2018 Lumpectomy, IDC w/tubulur features, 16mm tumor "no lymphovascular invasion identified", ki67 1-2% but 1/5 nodes (SLNB) had macrometasis of 2.1mm.
 Asked: 1/24/2018 Are there non-invasive ways to diagnose cancer cells in lymph nodes without all the damaging surgery in the axilla? It seems like this would be...
 Asked: 1/22/2018 WHAT DOES KI-67{< OR = 20% -SAYS FAVORABLE ---THEN UNDER UNFAVORAGLE SAYS kI-67>40%} AND ALSO WHAT IS HER-2/NEU- favorable 0 or 1+---BORDERLINE 2+---AND unfavorable...
 Asked: 1/18/2018 What does it mean ER diffusely positive, CK 5/6 focally absent and p63 retained around ducts? Thanks..
 Asked: 1/16/2018 What does a Ki-67 score of 5.8 mean?
 Asked: 1/16/2018 How do cancer cells get to the axillary lymph nodes? What method of transport do they use to get there? Blood? Lymph...
 Asked: 1/13/2018 How can DCIS NON INVASIVE STATE 0 BUT REOCURRING TREATED WHEN IT IS DEEMED NOT ESTROGEN RECEPTIVE BUT THE FIRST TIME THE dcis WAS estrogen...
 Asked: 1/12/2018 I have been diagnosed with a reocurring of dcis-stage o agai and non invasive-in the same area as 2016.
 Asked: 1/10/2018 what is well differentiated invasive ductal carcinoma with calcifications (tubule formation 2/3, nuclear pleomorphism 2/3, mitotic counts 1/3), measuring 1.3 cm in maximal
 Asked: 1/7/2018 Diagnosed with 2cm Grade 2/3 DCIS, .35cm IDC, grade 2, ER+, PR+, HER2-, had 2 sentinel nodes removed and found isolated tumor was in one...
 Asked: 1/7/2018 How can clean margins be obtained if the SLN nodes (2/3) are positive with lymphovascular invasion?
 Asked: 1/6/2018 I had a lumpectomy and SNB, 1/3 positive nodes.
 Asked: 1/4/2018 My stereotactic breast biopsy is undergoing receptor test now, and I am waiting for the testing result.
 Asked: 1/3/2018 If you could please explain what the following means it would be appreciated: DIAGNOSIS: Breast, right, core needle biopsy: -Benign fibroglandular mammary tissue (please see microscopic description) -Microcalcifications identified MICROSCOPIC...
 Asked: 1/1/2018 You and this site have been a godsend to me.
 Asked: 12/30/2017 I have had three opinions and still no clear answer.
 Asked: 12/30/2017 R breast nodule metaplastic carcinoma 7 MM.
 Asked: 12/27/2017 Had surgery by VA with partial penectomy.
 Asked: 12/21/2017 I’m surprised they use the terminology “approaches the threshold for DCIS”, isn’t it one or the other ADH or DCIS? I''m assuming there are concerns...
 Asked: 12/16/2017 Oct-2012: DCIS right breast, grade 3, ER+ PR- TX: Lumpectomy, 35 radiations, 5 years Exemestane Oct-2017: DCIS right breast, same location, grade 3, comedy type, size upto...
 Asked: 12/15/2017 The pathology report does not clearly state (so I can understand) whether the FISH test finds her2 + or Her2 -.
 Asked: 12/15/2017 ‘Is a Ki-67 an expected result with a core and/or surgical biopsy? I don’t have one on either of my reports..
 Asked: 12/15/2017 I was diagnosed with "ductal carcinoma, 1.3 cm with tubular and invasive cribriform patterns, modified bloom richardson grade 1 of 3.
 Asked: 12/13/2017 What does Nottingham score 8, stage PT1c, glandular differentiation 3, Nuclei 3, Mitosis 2, size 1.3cm, estrogen receptor: positive(99% strong) , Progesterone receptor Positive (95%...
 Asked: 12/13/2017 Hello. I was just diagnosed with Invasive Ductal Carcinoma with Micropapillary Features.
 Asked: 12/11/2017 Hello, I am a young 31 women who diagnosed last year with breast cancer.
 Asked: 12/9/2017 Sternal mets on CT & bone scan and pre-sternal nodule which was biopsied.
 Asked: 12/4/2017 What does the following from my pathology report mean: Distance of DCIS from closest Margin: Per the consultation report from Mayo Clinic,...
 Asked: 12/4/2017 Age 48. Mother had mastectomy at 42 and 48, passed at 63, I had a Mam 11/6, Compression Mam 11/7, Radiologist pointed out a single cluster of microcalcifications that was an area of concern due to the fact that it was a "single" cluster and the way they were clustered.
 Asked: 11/30/2017 Focal asymmetry on mammogram. U.S.
 Asked: 11/30/2017 Hello. Can you explain how important LVI is to prognosis? I had a small (9mm) tumor, strongly ER and PR+, HER2-, but lymphovascular invasion was identified.
 Asked: 11/30/2017 Dear Lillie, 1. My HMO surgical sample was not retested to confirm my ER, PR, HER2 and Ki-67 by my HMO or with the Oncotype DX/Genomic Health, score of 20.
 Asked: 11/29/2017 does oncotype dx consider focal lymphvascular invasion when they calculate the score ? .
 Asked: 11/29/2017 would you mind explaining focal lvi to me.
 Asked: 11/28/2017 How does the PR affect outcome? I am ER+, PR- and HER2-.
 Asked: 11/28/2017 DMG - THORACIC ........................... Nature of Material Right lung mass biopsy FINAL HISTOPATHOLOGY REPORT 28-11-2017 Gross Description Received multiple cores aggregating to 1x0.8cm submitted entirely. Microscopic Description Right lung mass biopsy: Adenocarcinoma. Intracellular mucin is...
 Asked: 11/27/2017 I just had bilateral mastectomy and all the doctors were happy with the pathology report which showed a 2 cm IDC, 0/2 nodes negative,...
 Asked: 11/26/2017 I had grade 2/3 mixed ductal/lobular, 1.5cm with focal LVI (lymph)and ki67% of 19.
 Asked: 11/25/2017 My pathology report says I have triple negative invasive ductal carcinoma grade 2 with prominent apocrine features and minor component of ductal carcinoma in situ,...
 Asked: 11/22/2017 Hello , my aunt was diagnosed with breast cancer in 2012.
 Asked: 11/21/2017 The 1st surgery report said 3 margins were DCIS positive, the 2nd surgery removed 3 pieces tissue for new margins.
 Asked: 11/13/2017 The first surgery was done in this June, pathology lab result were: INVASIVE CRIBRIFORM ADENOCARCINOMA associated with IPA + DCIS.
 Asked: 11/10/2017 My Mom had a lumpectomy on 10/17/2017.
 Asked: 11/8/2017 Hi Lillie. I have a question about the question that was just asked about being highly estrogen positive.
 Asked: 11/7/2017 Some studies have shown that women with high estrogen levels in their breast cancer have twice the chance for a recurrence than women with lower...
 Asked: 11/3/2017 Biopsy pathology report for testing of PR states "technically inadequate".
 Asked: 11/1/2017 Good morning. My pathology report says "paraductal inflammation with microcysts" this to me sounds like mastitis.
 Asked: 10/31/2017 I am a 63 year old female 2 weeks post bilateral mastectomy with sentinel node biopsy due to malignant neoplasm of right breast - ILC.
 
 
 
 
 

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