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AskedPublicly Submitted Question
05/11/2003My sister, age 32, was diagnosed with BC 4 years ago, had mastectomy with reconstruction. She did not get any adjuvant treatment. Now she had a recurrence in the muscle above the implant that was removed in surgery. She is scheduled for chemotherapy. Her ER and PR are positive. Due to the risk of infertility in the Chemo she would like to freeze eggs. Is there a risk in an IVF treatment (which means elevating the Estrogen levels for a short period)?
RepliedJHU's Breast Center Reply
05/12/2003We don't know and for this reason women are usually discouraged from doing so. We also don't know a great deal about the effects of hormone receptor positive tumors on future pregnancies. Though studies aggregately show that there isn't an increase in mortality, there certainly are women who you may hear about who had babies later and during the pregnancy were diagnosed yet again. Others of course do fine. I suspect she will be steered away from measures to elevate her estrogen at this time knowing that estrogen feeds her cancer. sorry. wish i had better news. Don't assume that chemo will guarantee infertility either. most women resume their periods post chemo today, particularly since we no longer do bone marrow transplants for breast cancer.

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