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ADH - Atypical Ductal Hyperplasia
Questions about atypical ductal hyperplasia.
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AskedPublicly Submitted Question
4/27/20112008- Calcs on mammo, ADH on core bx, and then ADH confirmed on Excisional Bx. 2011-same thing all over again. In 2007 I was offered Tamoxifen and declined because of what I read. No one really explained anything to me. (Shame on them) I'm sure after my ex bx this time, Tam will be offered again. What does data say about reducing calcs or ADH? Will ADH eventually become DCIS or is DCIS a separate entity? For the s/e of blood clots/stroke with Tam, could one take a baby asa a day to thin the blood? If you had no symptoms of hot flashes during menopause-could this be a good sign that you may not get hot flashes while on Tam. 50 yrs old, fit, on no Rx meds. TAM responds to estrogen + tissue, should I ask my breast surg to test my tissue when the next excisional bx is done to see if it is estrogen = or-?????? Last question, can you request yearly transvaginal ultrasonograhy for monitoring of endometrial changes/uterine changes or is this not standard of care? Thank you :)
RepliedJHU's Breast Center Reply
4/28/2011Thank you for writng to us. First, ADH atypical ductal hyperplasia is not cancer, but if the small amount of ADH grows to a larger amount, could then be classified as DCIS (ductal carcinoma in situ). Make an appointment with a medical oncologist to discuss with you, treatment for someone who is considered more high risk due to the history of ADH. Could be tamoxifen, could be an aromatase inhibitor since appears you are post menopausal?

ER expression is present in atypical hyperplasias and in situ carcinomas, so you could request testing. We also know that ER expression increases with age of pt at diagnosis.

Best wishes.

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