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LCIS - Lobular Carcinoma In Situ Questions about lobular carcinoma in situ. |
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| 7/1/2011 | In Jan. 2007 at age 59 I was diagnosed with left breast in situ and infiltrating lobular carcinoma, moderately differentiated. ER/PR positive. the tumor was 1.5cm, grade 2, mitotic grade intermediate. No vascular invasion. Sentinel node was believed cancer free on frozen section but later revealed involvement by ILC. Underwent a left axillary dissection that showed micrometastatic ILC in 1 of 7 nodes. It was AI1/3 pos and Her-2 neg. I had a T1cN1MO disease, stage IIa. On reading through some of your previous answers on the LCIS board I was surpised to read that patients with both an invasive carcinoma and LCIS have a rate of ~75% of developing cancer in the other breast. I was never told this statistic. You wrote that some women undergo mastectomies because of this. Should I have considered doing this. When the radiologist put in the markers for my lumpectomy he told me I should be having a mastectomy but my surgeon adamantly disagreed. 75% seems like high risk to me and after 4 years I am confused and worried about recurrence. I had 4 rounds of AC and 4 rounds of Taxol followed by radiation and Aromasin. | ||
| Replied | JHU's Breast Center Reply | ||
| 7/1/2011 | Timing is everything, isn't it?? more recently, data has been re-reviewed and found that having invasive lobular carcinoma in one breast doesn't increase risk for the other breast or "mirror image" itself with invasive lobular carcinoma over time. you are now 4 years out. that's great to hear!! your risk of local recurrence is quite low now and risk for the other healthy breast should be around 5% which is also quite low. be well. be optimistic. hormone receptor positive, HER2 negative also are great prognostic factors to have. | ||
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