Ask an Expert is a free question-and-answer service about breast cancer and breast health that is available on weekends. If you'd like to ask a question or comment, please visit us again on Saturday or Sunday. In the meantime, please search the existing topics using the search tool at the top of the page. It's quite possible that one of our many existing topics already addresses your question.
If you would like a consultation with a breast specialist at the Johns Hopkins Avon Foundation Breast Center, call 443-778-2778. It is possible to get an appointment for a second opinion within a few days of contacting us.
We hope you find the information helpful!
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Risk factors for Breast Cancer Questions about breast cancer risk. |
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| 10/17/2011 | Greetings. I am a 53 year old per-menopausal woman who based on family history and other factors is considered right at the borderline of being deemed "high risk" for breast cancer. I just squeaked in (statistically speaking) as a candidate for prophylactic tamoxifin therapy, for purposes of reducing my risk profile. I have been taking prophylactic tamoxifin for approximately one year. I am also prescribed Welbutrin XL (300 mg) for anxiety. I just stumbled across the literature suggesting that Welbutrin blocks the proper metabolism of tamoxifin in the liver, rendering the latter less effective. What is the status of the research on this, and should I strongly consider weaning off Welbutrin (under the direct supervision of my internist and ob/gyn)? Any evidence-based input you could provide on this topic would be greatly appreciated. | ||
| Replied | JHU's Breast Center Reply | ||
| 10/17/2011 | ask your oncologist to do a CYP2D blood test to see if the compatibility of these drugs in your particular situation is an issue for metabolism and absorption. | ||
Please note: This service is not intended to provide primary medical advice concerning specific medical care or treatment. Ask an Expert is a free service operated by health care professionals at the Johns Hopkins Avon Foundation Breast Center. Due to the volume of questions and their complexity, there are times when medical oncologists, surgeons, radiation oncologists or oncology nurses are consulted for their input. These individuals volunteer their time for this service and will respond as soon as they are able. Please do not post or send the same question to us in multiple locations or categories.