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Concerns about Breast Cancer Family History
Questions on genetics, family history & breast cancer.
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AskedPublicly Submitted Question
10/21/2011My mother passed away from breast cancer at the age of 38, her sister at 41, and their mother (my grandmother) at 52. My father died of prostate cancer, and I lost my brother to prostate cancer earlier this year.

I am 49. In the last year I have had 4 Stereo-tactic biopsies and 1 excisional surgery resulting in a diagnosis of LCIS, ADH and ALH. I am meeting with a genetics counselor on Monday, but I have 2 questions for you:
1. If all family members have passed away, can they still do Genetic testing? (I heard somewhere that they couldn't).
2. I am seriously considering double mastectomy with reconstruction(Prophylactic) In your honest opinion, do you think this is too drastic?

Thank you for providing this wonderful service!
RepliedJHU's Breast Center Reply
10/21/2011Thank you for turning to the Johns Hopkins Breast Center with your questions. My goodness, that is a very compelling family history! While we would first test those with breast cancer, it is fine and advisable for you to be tested, since your relative are deceased. In addition, consult with a breast medical oncologist regarding risk reduction measures such as tamoxifen. It does not sound too drastic for a double mastectomy if this feels comfortable to you. Every one is different and there is no 'right' answer...just the decision you make based on education and your own comfort level-your right decision! Consult with a breast plastic reconstructive surgeon as well. Here we routinely do the DIEP flap, which uses your own tissue (tummy fat and skin) but does not touch the abdominal muscle. We also perform implant reconstruction as well. If we can be of help, please call Sheila @ 443-287-BRST (2778) for an appointment. Hope this helps and best wishes.

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