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Understanding Pathology Results Questions explaining and understanding pathology results. |
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| 11/15/2011 | Hello my mother, age 70, was just diagnosed with high grade infiltrating ductal carcinoma. a tru-cut biopsy was performed and here are the results: sections demonstrate an invasive neoplasm w/poor tubule formation(3pts), marked cytologic atypia(3 pts) & increased miotic activity (15mits/10hpf)(3pts. this is an SBR III.Immunoperoxidase stains were performed & evaluated w/the following results: Ki-67: ~60% ER: strongly positive in >90% PR: strongly positive in ~30% Her2Neu: equivocal (2+) the specimen will be sent for heu2neu testing by FISH& those results will be subsequently reported. What exactly does this mean? we are seeking a second opinion and would like to know what questions we will need to ask the new doctor. | ||
| Replied | JHU's Breast Center Reply | ||
| 11/16/2011 | The breast cancer appears to be a bit aggressive from the perspective of its proliferation rate-- that's the Ki 67. It's great that its strongly positive for Estrogen receptors. The measurement of the tumor would be on the mammogram report. that's important to know as it helps guessimate her stage. infiltrating ductal carcinoma is the most common type of breast cancer. time to see a breast surgical oncologist and discuss surgical recommendations. if you would like to bring her here you are welcome to do so. 443-287-2778. I'm hoping it is relatively small and she would be a candidate for lumpectomy surgery with sentinel node biopsy. | ||
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