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LCIS - Lobular Carcinoma In Situ
Questions about lobular carcinoma in situ.
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AskedPublicly Submitted Question
2/22/2012I was just diagnosed with Pleomorphic LCIS. The pathology report states LCIS exhibits grade 2-3 nuclei. E-cadherin stains document decreased to absent membrane straining consistent with LCIS. This high grade lobular carcinoma in situ is also called pleomorphic LCIS. This variant extends to superior and posterior margins. My surgeon did not have a lot of information about this, however on the pathology report , it stated to treat like DCIS Not understanding why, since I was told my diagnosis is not cancer. Do you have any information on pleomorphic LCIS and why they would be treating it in this manner?
RepliedJHU's Breast Center Reply
2/22/2012that does't make sense to me either. i think it would be wise to have the pathology slides themselves re-reviewed by a breast pathologist elsewhere for a second opinion. if you want that done with us just call 443-287-2778 and sheila will tell you how to make that happen. LCIS isn't cancer and doesn't require free margins.

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