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LCIS - Lobular Carcinoma In Situ
Questions about lobular carcinoma in situ.
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AskedPublicly Submitted Question
4/19/2012This is a terrific resource, thank you for providing it.
I'm 54 and was diagnosed with LCIS about a year ago with a needle biopsy followed by an excisional biopsy. A couple of months before that, I had surgery for Stage I endometrial cancer and Stage I colon cancer (grandmother, mother, cousins...all familial). I've since had genetic testing and tested positive for HNPCC.
Although breast cancer isn't usually considered one of the HNPCC/Lynch cluster cancers, I have been told that the LCIS along with Lynch elevates my risk to high and that they want to begin screening me as if I am high risk with yearly breast MRIs and ultrasounds. I already am in high-risk screening for colon and other related HNPCC cancers. Does the newest research show possible connections between HNPCC and breast cancer? Thank you.
RepliedJHU's Breast Center Reply
4/19/2012Actually, yes, there is more recent research that implies there is a link. Go to two sites to read about this more-- http://fightcolorectalcancer.org/research_news/2010/07/is_breast_cancer_linked_to_lynch_syndrome

as well as to www.hopkinsbreastcenter.org/artemis and use the search feature there.

So consider genetic counseling regarding this would be useful. Don't be surprised if in your specific case, which is not the case for others with LCIS, that you are advised to do bilateral prophylactic mastectomies with reconstruction. if you decide to pursue that step feel free to come to us. 443-287-2778.

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