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|Forum||Questions||Ask a Question|
Questions about Neoadjuvant and Adjuvant Chemotherapy.
|Asked||Publicly Submitted Question|
|5/16/2012||Blood/Lymphatic Vessel Invasion was absent/not observed. Grade 3, Stage 11A,T1c, N1 Mo. Er Receptor High Positives and the PR receptor high. Ki67 High Proliferation index (36%) Surgeon said he got it all margins clear. Took out 12 nodes one was positive.And no evidence of malignancy in 11 Lymph Nodes.Sould I have chemo or not.|
|Replied||JHU's Breast Center Reply|
|5/16/2012||there are many factors used to determine chemotherapy recommendations today. HER2 receptor being a key one and your age being another. doesn't matter that there asn't blood/lymphatic vessels seen in the tumor because it did still manage to get to the nodes, thus your sentinel node contained cancer cells. if HER2 is negative then ask the oncologist if he/she used oncotypeDX as a way to provide more information regarding whether chemo would be of benefit or if hormonal therapy will be the only systemic treatment recommended.|
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