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Hormonal Therapy Questions about Hormonal Therapy. |
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| Asked | Publicly Submitted Question | ||
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| 5/21/2012 | I received neoadjuvant therapy for a Her2+, 6cm+ tumor. I had a pathological complete response with no lymph node invasion, no residual or prior tumor found after single mastectomy. At the time of original biopsy, my tumor stained 50% weak to moderate for estrogen in addition to Her2+. I will continue 1 year herceptin treatments, but have refused radiation. My oncologist believes that 5 year Arimidex is necessary to reduce reoccurence....my question is..How much does Arimidex actually reduce risk in a weak to moderate ER+/HER2+ tumor, especially in someone who is already continuing Herceptin? I have read so many conflicting reports, including some that say that Arimidex could actually fuel the cancer in Her2+ patients...Please advise... | ||
| Replied | JHU's Breast Center Reply | ||
| 5/22/2012 | it isn't known exactly since studies aren't able to be broken down by the % of positivity that a tumor has. congrats on complete pathological response. that is rare and wonderful. sounds like however your doctor wants to ensure as best as possible that this disease doesn't recur and and given its size and HER2 positivity and partial hormone receptor positivity, it makes sense that he/she would recommend taking everything possible to prevent it from coming back. | ||
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