Ask an Expert is a free question-and-answer service about breast cancer and breast health that is available on weekends. If you'd like to ask a question or comment, please visit us again on Saturday or Sunday. In the meantime, please search the existing topics using the search tool at the top of the page. It's quite possible that one of our many existing topics already addresses your question.
If you would like a consultation with a breast specialist at the Johns Hopkins Avon Foundation Breast Center, call 443-778-2778. It is possible to get an appointment for a second opinion within a few days of contacting us.
We hope you find the information helpful!
|Forum||Questions||Ask a Question|
Questions about Hormonal Therapy.
|Asked||Publicly Submitted Question|
|5/21/2012||I received neoadjuvant therapy for a Her2+, 6cm+ tumor. I had a pathological complete response with no lymph node invasion, no residual or prior tumor found after single mastectomy. At the time of original biopsy, my tumor stained 50% weak to moderate for estrogen in addition to Her2+. I will continue 1 year herceptin treatments, but have refused radiation. My oncologist believes that 5 year Arimidex is necessary to reduce reoccurence....my question is..How much does Arimidex actually reduce risk in a weak to moderate ER+/HER2+ tumor, especially in someone who is already continuing Herceptin? I have read so many conflicting reports, including some that say that Arimidex could actually fuel the cancer in Her2+ patients...Please advise...|
|Replied||JHU's Breast Center Reply|
|5/22/2012||it isn't known exactly since studies aren't able to be broken down by the % of positivity that a tumor has. congrats on complete pathological response. that is rare and wonderful. sounds like however your doctor wants to ensure as best as possible that this disease doesn't recur and and given its size and HER2 positivity and partial hormone receptor positivity, it makes sense that he/she would recommend taking everything possible to prevent it from coming back.|
Please note: This service is not intended to provide primary medical advice concerning specific medical care or treatment. Ask an Expert is a free service operated by health care professionals at the Johns Hopkins Avon Foundation Breast Center. Due to the volume of questions and their complexity, there are times when medical oncologists, surgeons, radiation oncologists or oncology nurses are consulted for their input. These individuals volunteer their time for this service and will respond as soon as they are able. Please do not post or send the same question to us in multiple locations or categories.