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Concerns about Breast Cancer Family History
Questions on genetics, family history & breast cancer.
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AskedPublicly Submitted Question
11/21/2015Wondering about breast (and other) cancer in multiple generations on my mom's side. My aunt and two of her 1st cousins all premenopausal breast cancer, my grandmother (though very elderly) and two of her sisters at late 50s and 60s with breast cancer. Two of my grandmother's sister's sons died of prostate cancer (40s). Another one of my maternal aunts had uterine cancer. I have a 3rd maternal cousin just diagnosed with breast cancer dx 53. Now I have breast cancer at 59.I have tested negative for brca genes and palb2. Genetic counselor says results should be viewed with caution because of this family history. Does it sound like there could be an unidentifiable breast cancer gene in my family? How likely could that be? Does that mean I would have higher chance of new primary cancer in other breast?
RepliedJHU's Breast Center Reply
11/21/2015sure sounds like a gene is at work in your family. so you should consider yourself high risk whether testing positive for the genes that we have a way of testing for. there are other genes that lack ways of testing today. that is what your family may have.

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