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Complementary Medicine
Questions about Integrative and Complementary Medicine
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AskedPublicly Submitted Question
2/15/2016What exactly is I3C? My Naturalalpathic Physician recommended the I3C. She said it effects the estrogen conversion in my body. I had a mastectomy because of an estrogen driven tumor. There was no lymph node involvement and the margins were clear. My OncoTX score is 19. because of other health factors - Parkinson's, Osteoporosis, fibromyalgia and a sleep disorder - I have not tolerated the conventional aroma taste inhibitors well at all.

When exactly is the I3C used in the treatment of the above breast cancer. I would like to have this information before I speak with my medical oncologist.

Thank you for your service and information.

RepliedJHU's Breast Center Reply
2/16/2016There is not evidence based statistical research conducted at cancer centers to provide information whether I3C is of benefit or not. Indole-3-carbinol (IC3) itself is a byproduct of glucosinolate glucobrassicin, which is a compound found in all cruciferous vegetables, such as: broccoli, cauliflower, cabbage, brussel sprouts, kale, and the like. I am not aware of any situation where it has been used for breast cancer treatment or as a substitute for hormonal therapy.

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