Ask an Expert: View a Question
 
 
 
 

Ask an Expert is a free question-and-answer service about breast cancer and breast health that is available on weekends. If you'd like to ask a question or comment, please visit us again on Saturday or Sunday. In the meantime, please search the existing topics using the search tool at the top of the page. It's quite possible that one of our many existing topics already addresses your question.

If you would like a consultation with a breast specialist at the Johns Hopkins Avon Foundation Breast Center, call 443-997-8282. It is possible to get an appointment for a second opinion within a few days of contacting us.

We hope you find the information helpful!

ForumQuestionsAsk a Question
Complementary Medicine
Questions about Integrative and Complementary Medicine
722 Ask a Question

AskedPublicly Submitted Question
2/15/2016What exactly is I3C? My Naturalalpathic Physician recommended the I3C. She said it effects the estrogen conversion in my body. I had a mastectomy because of an estrogen driven tumor. There was no lymph node involvement and the margins were clear. My OncoTX score is 19. because of other health factors - Parkinson's, Osteoporosis, fibromyalgia and a sleep disorder - I have not tolerated the conventional aroma taste inhibitors well at all.

When exactly is the I3C used in the treatment of the above breast cancer. I would like to have this information before I speak with my medical oncologist.

Thank you for your service and information.

Laurel
RepliedJHU's Breast Center Reply
2/16/2016There is not evidence based statistical research conducted at cancer centers to provide information whether I3C is of benefit or not. Indole-3-carbinol (IC3) itself is a byproduct of glucosinolate glucobrassicin, which is a compound found in all cruciferous vegetables, such as: broccoli, cauliflower, cabbage, brussel sprouts, kale, and the like. I am not aware of any situation where it has been used for breast cancer treatment or as a substitute for hormonal therapy.

Please note: This service is not intended to provide primary medical advice concerning specific medical care or treatment. Ask an Expert is a free service operated by health care professionals at the Johns Hopkins Avon Foundation Breast Center. Due to the volume of questions and their complexity, there are times when medical oncologists, surgeons, radiation oncologists or oncology nurses are consulted for their input. These individuals volunteer their time for this service and will respond as soon as they are able. Please do not post or send the same question to us in multiple locations or categories.

The contents of this portion of the website cannot be used as a substitute for a consultation with your doctor or other healthcare provider. It also may not represent the opinions of other Johns Hopkins professionals. It is a free service performed on volunteer time and intended to provide feedback to questions posted by consumers however should not be used as a directive or instructions to now follow. Seeing your own medical provider is always important in getting your needs and questions addressed. In the majority of cases, a clinical examination, review of pathology slides and xrays, along with other medical information is needed to truly provide a consultative service. If you wish to receive a formal consultation with our physicians please call 443-997-8282 for surgical appointments and 410-955-8964 for medical or radiation oncology appts. For breast imaging, call 410-955-4100.

 
 
 
 
 

© The Johns Hopkins University, The Johns Hopkins Hospital, and Johns Hopkins Health System, All rights reserved.