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Concerns about Breast Cancer Family History
Questions on genetics, family history & breast cancer.
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AskedPublicly Submitted Question
2/16/2016I am 42 years old, never had children. My mother died of inflammatory breast cancer at age 58. My sister had atypical hyperplasia and had a subcutaneous double mastectomy at age 36. My mother's sister had stage 3 breast cancer at age 70. My dad's sister died at age 42 of breast cancer. My mother's grandmother died of breast cancer. Given the family history I have had a BRCA test done and I am negative for carrying the gene. My most recent mammogram showed that I had breast calcifications that had changed since my last mammogram last year. I was supposed to follow up in six months but my insurance changed. They are now sending me for a stereotactic biopsy. I have previously had a fibroadenoma removed out of the same breast. I have a history of cysts and dense breast tissue. What is the likelihood this could be cancer and how quickly will I get the results? The calcifications are found throughout my breast. Will they take more than one sample?
RepliedJHU's Breast Center Reply
2/16/2016if this is a cluster of microcalcifications and they have increased in number since prior mammograms then there would be a good chance this may be an early stage breast cancer. though you tested negative for the known breast cancer genes, you still may have a gene that hasn't been discovered yet to enable testing to be done. your family history is compelling. they should be taking 5-6 samples.

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