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Concerns about Breast Cancer Family History
Questions on genetics, family history & breast cancer.
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AskedPublicly Submitted Question
6/23/2016I am 4rh generation breast cancer patient, 3C. My sister stage 0. Both negative for BRCA gene. Any research or options available for our families? I attended nursing school w/Lillie for short time in 1971/72.
RepliedJHU's Breast Center Reply
6/24/2016And this is Lillie who is answering your posting here! Though your family tested negative for BRCA mutations your family definitely has something genetically going on. If the testing was done prior to 2012, consider returning for more testing because there are more genes that have been identified that may be one of the ones your family has. Very reasonable for family members to consider taking tamoxifen for prevention. Those who are particularly worried are likely even eligible for even doing preventative surgeries too. most important to take measures in general to reduce risk. no HRT. no smoking. very limited alcohol consumptions. keep weight in normal range. diet low in fat and high in orange and green veggies. hang in... Though your sister was stage 0, yours you mentioned was 3C which carries a high risk of distant and local recurrence as you no doubt know. you should be followed closely by breast cancer specialists.

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