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ADH - Atypical Ductal Hyperplasia
Questions about atypical ductal hyperplasia.
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AskedPublicly Submitted Question
7/12/2017Hi. I am a 46 year old female and recently had an abnormal mammogram and ultrasound of the left breast. My mother is a 20 year, stage 1 breast cancer survivor (post menopausal). No other relatives with breast cancer.

Stereotactic biopsy was benign and identified sclerosing adenosis. As the surgeon felt this diagnosis sometimes keeps "bad company" he scheduled an excisional biopsy with the following pathologic diagnosis:

-Intraductal papilloma with atypical ductal hyperplasia, sclerosis and micro-calcifications (atypical papilloma), completely excised
-multifocal atypical ductal hyperplasia
-multifocal micropapillomatosis
-extensive fibrocystic changes with columnar cell change, adenosis and micro-calcifications
-pseudoangiomatous stromal hyperplasia

Based on the NCI Breast Cancer Risk Assessment tool: I was also told my 5 year risk of developing breast cancer is 4.8% versus the average 1% and my lifetime risk for developing breast cancer is 36.6% versus the average of 11.8%

I am scheduled for a consult with a medical oncologist re: the pros and cons of tamoxifen. I am newly married, have no menopausal symptoms, and in otherwise good health so I am concerned about the side effects of tamoxifen. But, on the other hand, I am also concerned about not taking action and ending up with invasive breast cancer.

Do the benefits outweigh the risk given my situation?
RepliedJHU's Breast Center Reply
7/12/2017Good that you are seeing a medical oncologist to discuss this further. ADH is a risk factor for getting breast cancer one day. some women opt to take tamoxifen to reduce this risk and others opt for close surveillance instead. tamoxifen carries overall a low risk of complications.

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