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Breast Abnormalities and Other Symptoms
General questions about breast health and possible symptoms.
14,644 Ask a Question

AskedPublicly Submitted Question
7/19/201756 y/o female newly diagnosed with Stage 0 DCIS grade 3, solid type with apocrine and squamous metaplasis with central necrosis and microcalifications. ER/PR negative.Path report findings: P63 does not show evidence of invasive carcinoma, Ki-67 shows high proliferation fraction raging from 5-40% in atipical glands. There are focal giant cell reactions to the squamous cell metaplasia.

Treatment options given: lumpectomy with radiation or mastectomy with no radiation. MRI to be done prior to surgery to check for the other potential lesions not found. Her2 status unknown.

Questions: With this type of cancer and tumor grade what is the likelihood of positive axillary nodes?

Is there an alternative to Tamoxifen for double negative or triple negative tumors?

What is the recurrence rate of cancer after lumpectomy with radiation vs mastectomy?

My concern with this diagnosis I fell into the 20% range of calcifications being postive for cancer in addition I am in the 44% of women her are ER/PR negative.

THANK YOU for this forum and your attention to my questions!
RepliedJHU's Breast Center Reply
7/19/2017less than 1%

no, not at this time

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