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Concerns about Breast Cancer Family History
Questions on genetics, family history & breast cancer.
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AskedPublicly Submitted Question
8/5/2017I am 53. Found out a month ago that I have the BRCA2 mutation. Had salpingo oopherectomy done last Friday. Grandmother had breast removed at age 40 due to cycsts and then was diagnosed with BBC at age 60 (this was 40 years ago). My mother had atypical hyperplasia at age 60 and was on tamoxifen for 5 years. The next year she was diagnosed with lobular cancer in the other breast (10 years ago) I have had a lump in my lower right armpit for 2 years. Ultrasound showed lymph nodes measuring 1.4x1.3x.o in size, thickened core up to 5mm (bi-rads category acr4). Biopsy done and showed lymphocytes consisting of centrocytes and centroblasts, rare tingible body histocytes, recommended excision ifmclinically indicated. Surgeon did not feel necessary to remove. Another ultra sound was done 6 months later, 1.7x.9x1.4, fatty hila are preserved in lymphnodes. Said no significant change from prior, bi-rads acr2 benign finding. Because my mothers breast cancer was only detected by MRI, had one last fall. Findings, no enlarged axillsry or internal mammy lymphnodes. Bi-rads acr1, although I question if that could clearly see my lump in armpit. I also have had a larger lump in my upper armpit, which I've thought might be a lipoma. Fast forward to this summer and finding out I have BRCA2 mutation. Have an appointment with a breast surgeon next week and am contemplating my next step, monitor, prophlatic bi-lateral mastectomy. I won't consider tamoxifen since it did not seem to be effective with my mother. My breast density on all my mammograms bi-rad3. My follow up mammograms have been clear but they were normal mammograms and not ones to specifically check my right breast and armpit. Would appreciate any thoughts.
RepliedJHU's Breast Center Reply
8/5/2017most women opt for bilateral prophylactic mastectomies with reconstruction. otherwise tamoxifen will be pushed hard, more than likely.

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